Analysis of population-based colorectal cancer screening in Guangzhou, 2011-2015
Analysis of population-based colorectal cancer screening in Guangzhou, 2011-2015
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2011-2015年广州市人群结直肠癌筛查分析
DOI：
10.1002/cam4.1867
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发表时间：
2019-05-01
期刊：
影响因子：
4
通讯作者：
Zhao DeJian
中科院分区：
文献类型：
--
作者：
Feng Zhiqiang;Cao Jie;Zhao DeJian
目的分析广州市人群结直肠癌及息肉的筛查结果。方法2011年1月至2015年12月，抽取30-79岁居民进行结直肠癌筛查。对居民进行问卷调查和/或FOBT评估高危人群，推荐免费肠镜检查，并对结果进行详细评价。结果共筛查居民98 927人，检出高危人群5 306人（男1 859人，女3 447人），结肠镜检查4713人（男1 690人，女3 023人）。55例（男28例，女27例）大肠癌，男性检出率高于女性（P = 0.019）。随着年龄的增长，60岁以上人群的检出率明显高于60岁以下人群（x（2）= 18.64，P = 0.000924）。息肉1458例（30.94%）。病理检查1420例（腺瘤971例，非腺瘤性息肉449例）。晚期腺瘤462例（男240例，女222例），非晚期腺瘤509例（男255例，女254例）。晚期腺瘤男性检出率高于女性（14.20%vs7.34%，P = 2.64 × 10 - 14）。不同年龄组腺瘤和晚期腺瘤的检出率，40岁以上组高于40岁以下组（20.91%vs3.61%，P = 7.87x10（-6）; 9.94%vs2.41%，P = 0.009）。结论广州市居民大肠癌和腺瘤的检出率分别为1.17%和20.60%。大肠癌检出率随年龄增长而增加，60岁以上人群大肠癌检出率明显高于60岁以下人群。但40岁以上人群中腺瘤和晚期腺瘤的检出率高于年轻人群。因此，对于40岁以上的人群，建议进行CRC筛查。
Objective To analyze the detection rates of colorectal cancer (CRC) and polyps by population-based screening in Guangzhou. Methods From January 2011 to December 2015, the residents aged 30-79 were selected for CRC screening. The residents were conducted Questionnaires and/or FOBT to assess high-risk groups, the free colonoscopy examination was recommended, and the results were evaluated in detail. Results There were 98 927 residents involving screening, 5306 high-risk residents identified (males 1859 and females 3447), and 4713 subjects underwent colonoscopy (males 1690 and females 3023). CRC was seen in 55 individuals (males 28 and females 27), and the detection rates in male were higher than in female (P = 0.019). And the detection rates increasing with age, for people over 60 years old, were obviously higher than those younger (x(2) = 18.64, P = 0.000924). The polyps were seen in 1458 (30.94%) cases? and 1420 subjects received pathological examination (adenomas 971 and non-adenomatous polyps 449). Advanced adenomas were seen in 462 cases (males 240 and females 222) and 509 cases of non-advanced adenomas (males 255 and females 254). For advanced adenomas, the detection rates in male were higher than female (14.20% vs 7.34%, P = 2.64 x 10(-14)). For the detection rates of adenomas or advanced adenomas by age, the people over 40 years were higher than younger (20.91% vs 3.61% P = 7.87 x 10(-6); 9.94% vs 2.41%, P = 0.009). Conclusions For Guangzhou residents, the detection rates of CRC and adenoma were 1.17% and 20.60%. The detection rates of CRC increasing with age, for people over 60 years old, were obviously higher than those younger. But for people over 40 years, the detection rate of adenoma and advanced adenoma was higher than younger. So for people over 40 years, the CRC screening is recommended.