THEORY FOR DISTORTION STUDIES OF LUNG PARENCHYMA BASED ON ALVEOLAR MEMBRANE PROPERTIES
THEORY FOR DISTORTION STUDIES OF LUNG PARENCHYMA BASED ON ALVEOLAR MEMBRANE PROPERTIES
复制标题
DOI：
10.1016/0021-9290(74)90074-8
复制
发表时间：
1974-01-01
影响因子：
2.4
通讯作者：
LEE, GC
中科院分区：
文献类型：
--
作者：
FRANKUS, A;LEE, GC
本文提出了一个反映肺微观结构的有限元模型。模型的分析产生关于肺实质的机械特性的信息。该模型所依据的微观特性是通过外推单轴数据计算的，该数据是从实验获得的离体肺的压力-体积关系计算的。宏观特性是通过将微观单元组装成肺实质结构，并分析其对非均匀力的响应而得到的，而有关肺的力学特性的实验资料是缺乏的，这种基于已知压力-容积关系的数学模型可以满足肺力学研究的需要。特别是，它为有限元分析中的单元刚度关系提供了完整的信息，模型特性与最近进行的宏观变形实验的比较表明，具有很好的相关性。
A finite element model reprensenting the microscopic structure of the lungs is presented. Analysis of the model yields information on the mechanical properties of the lung parenchyma. The micro-properties upon which the model is based are computed by extrapolating uniaxial data calculated from experimentally obtained pressure-volume relationships of excised lungs. Macro-properties are subsequently found by assembling the micro-elements into a parenchymal structure of the lung, and analyzing its responses to non-uniformly applied forces.Experimental information regarding the mechanical properties of lungs is lacking and this mathematical model which is based on the known pressure-volume relationships can fill a need in mechanical studies of the lungs. In particular, it provides the complete information for the element stiffness relationship in finite element analysis.Comparison of the model properties with recently conducted macro-level distortion experiments indicates very good correlation.