Semi-automatic segmentation of the placenta into fetal and maternal compartments using intravoxel incoherent motion MRI.
Semi-automatic segmentation of the placenta into fetal and maternal compartments using intravoxel incoherent motion MRI.
复制标题
使用体素内不相干运动 MRI 将胎盘半自动分割为胎儿和母体区室。
DOI：
10.1117/12.2254610
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Limperopoulos,Catherine
中科院分区：
文献类型：
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作者：
You,Wonsang;Andescavage,Nickie;Zun,Zungho;Limperopoulos,Catherine
体素内非相干运动(IVIM)磁共振成像是一种新兴的非侵入性技术，最近已被应用于体内整体胎盘血流灌注的量化。我们提出了一种健壮的半自动方法，从IVIM数据中分割出胎儿和母体的胎盘，使用一种名为GrowCut的多标签图像分割算法。胎盘IVIM数据采集在1.5T扫描仪上，取自16名孕周21-37周的健康孕妇。然后在非刚性图像配准后估计体素方向的血流灌注分数。利用结构T2加权参考图像确定胎儿和母体室的种子区域，并通过GrowCut算法的迭代过程逐步改进，以准确地包含胎儿和母体室。结果显示，胎盘血流灌注分数在胎儿室(−0.010/周)和母室(−0.013/周)均降低，而它们的相对差值(胎儿-母体)随着胎龄的增加而逐渐增大(+0.003/周，p=0.065)。我们的初步结果表明，所提出的方法在使用IVIM区分胎盘室是有效的。
Intravoxel incoherent motion (IVIM) magnetic resonance imaging is an emerging non-invasive technique that has been recently applied to quantify in vivo global placental perfusion. We propose a robust semi-automated method for segmenting the placenta into fetal and maternal compartments from IVIM data, using a multi-label image segmentation algorithm called ‘GrowCut’. Placental IVIM data were acquired on a 1.5T scanner from 16 healthy pregnant women between 21-37 gestational weeks. The voxel-wise perfusion fraction was then estimated after non-rigid image registration. The seed regions of the fetal and maternal compartments were determined using structural T2-weighted reference images, and improved progressively through an iterative process of the GrowCut algorithm to accurately encompass fetal and maternal compartments. We demonstrated that the placental perfusion fraction decreased in both fetal (−0.010/week) and maternal compartments (−0.013/week) while their relative difference (ffetal-fmaternal) gradually increased with advancing gestational age (+0.003/week, p=0.065). Our preliminary results show that the proposed method was effective in distinguishing placental compartments using IVIM.