Advances in managing acute pancreatitis.
Advances in managing acute pancreatitis.
复制标题
DOI：
10.3410/m1-59
复制
发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Debenedet AT
中科院分区：
文献类型：
--
作者：
Dimagno MJ;Wamsteker EJ;Debenedet AT
本文就近年来急性胰腺炎的研究进展作一综述。我们专注于AP的临床方面--尤其是严重疾病--以及指导患者临床护理的风险分层工具。大多数AP患者病情较轻，需要诊断评估、自限性支持治疗和短期住院。在潜在重度AP患者中，临床医生应使用现有的风险分层工具识别高危患者并及时采取干预措施，如积极的液体复苏、密切监测、早期肠内营养和适当使用内镜逆行胰胆管造影。这种方法降低了发病率和可能的死亡率，并得到了最近临床指南、历史文献和去年发表的最高质量研究的证据支持。
This review highlights advances in acute pancreatitis (AP) made in the past year. We focus on clinical aspects of AP - severe disease especially - and risk stratification tools to guide the clinical care of patients. Most patients with AP have mild disease that requires a diagnostic evaluation, self-limited supportive care, and a short hospital stay. In patients with potentially severe AP, it is important for clinicians to use available risk-stratifying tools to identify high-risk patients and initiate timely interventions such as aggressive fluid resuscitation, close monitoring, early initiation of enteral nutrition, and appropriate use of endoscopic retrograde cholangio-pancreatography. This approach decreases morbidity and possibly mortality and is supported by evidence drawn from recent clinical guidelines, historical literature, and the highest quality studies published in the last year.