Acute Stroke Imaging Research Roadmap IV: Imaging Selection and Outcomes in Acute Stroke Clinical Trials and Practice.

Acute Stroke Imaging Research Roadmap IV: Imaging Selection and Outcomes in Acute Stroke Clinical Trials and Practice.
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DOI:
10.1161/strokeaha.121.035132
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发表时间:
2021-08
期刊:
影响因子:
8.3
通讯作者:
STAIR XI Consortium
STAIR XI Consortium
中科院分区:
医学1区
文献类型:
--
作者:
Campbell BCV;Lansberg MG;Broderick JP;Derdeyn CP;Khatri P;Sarraj A;Saver JL;Vagal A;Albers GW;STAIR XI Consortium

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中风治疗学院行业圆桌会议(STAIR)于2020年10月1日至2日通过网络研讨会在STAIR XI期间赞助了一次成像会议和研讨会,以制定共识建议,特别是关于主要中风中心的最佳成像。该论坛汇集了中风神经学家,神经放射学家,神经影像学研究科学家,国家神经疾病和中风研究所(NINDS)的成员,行业代表和美国食品药品监督管理局的成员,讨论再灌注治疗的发展,特别是在延长的时间窗口中的成像优先事项,并重新激发了对脑细胞保护试验的兴趣。影像学会议总结和比较了最近急性卒中试验的影像学组成部分,并讨论了主要卒中中心的最佳影像学策略。成像研讨会提出了优化CT和MR急性卒中成像的采集、分析和解释的共识建议,以及初级卒中中心成像策略的建议。最近积极的急性卒中临床试验已经使用成像选择延长了再灌注治疗的治疗窗口。因此,实现快速和高质量的中风成像在初级和综合中风中心都至关重要。建议加强中风成像研究。
The Stroke Treatment Academy Industry Roundtable (STAIR) sponsored an imaging session and workshop during the STAIR XI via webinar on October 1–2, 2020 to develop consensus recommendations, particularly regarding optimal imaging at primary stroke centers. This forum brought together stroke neurologists, neuroradiologists, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), industry representatives, and members of the US Food and Drug Administration to discuss imaging priorities in the light of developments in reperfusion therapies, particularly in an extended time window, and reinvigorated interest in brain cytoprotection trials. The imaging session summarized and compared the imaging components of recent acute stroke trials and debated the optimal imaging strategy at primary stroke centers. The imaging workshop developed consensus recommendations for optimizing the acquisition, analysis and interpretation of CT and MR acute stroke imaging, and also recommendations on imaging strategies for primary stroke centers. Recent positive acute stroke clinical trials have extended the treatment window for reperfusion therapies using imaging selection. Achieving rapid and high quality stroke imaging is therefore critical at both primary and comprehensive stroke centers. Recommendations for enhancing stroke imaging research are provided.