HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women
HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women
复制标题
DOI：
10.1016/j.diagmicrobio.2012.09.009
复制
发表时间：
2013-01-01
影响因子：
2.9
通讯作者：
Thakar, Madhuri
中科院分区：
文献类型：
--
作者：
Mane, Arati;Kulkarni, Smita;Thakar, Madhuri
我们对阴道乳酸杆菌进行了定量，并确定了它们与生殖器 HIV-1 脱落的关系，发现乳酸杆菌数量减少与宫颈 HIV-1 病毒载量之间存在显着负相关（r(2) = - 0.8900，P < 0.01），这可能会增加 HIV-1 性传播和生殖器感染的机会。 (C) 2013 Elsevier Inc. 保留所有权利。
We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load (r(2) = - 0.8900, P < 0.01), which may have implications of increased chances of sexual transmission of HIV-1 and genital infections. (C) 2013 Elsevier Inc. All rights reserved.