Rethink Organization to iMprove Education and Outcomes (ROMEO): a multicenter randomized trial of lifestyle intervention by group care to manage type 2 diabetes.
Rethink Organization to iMprove Education and Outcomes (ROMEO): a multicenter randomized trial of lifestyle intervention by group care to manage type 2 diabetes.
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DOI：
10.2337/dc09-2024
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发表时间：
2010-04
期刊：
影响因子：
16.2
通讯作者：
ROMEO Investigators
中科院分区：
文献类型：
--
作者：
Trento M;Gamba S;Gentile L;Grassi G;Miselli V;Morone G;Passera P;Tonutti L;Tomalino M;Bondonio P;Cavallo F;Porta M;ROMEO Investigators
进行了一项试验，以确定我们的2型糖尿病生活方式干预的团体护理模式是否可以出口到其他诊所。本研究是一项在意大利13家医院糖尿病诊所进行的4年、双组、多中心对照试验（当前对照试验编号ISRCTN 19509463）。共有815名年龄<80岁、已知糖尿病病程≥1年的非胰岛素治疗患者被随机分配至组或个体治疗组。4年后，尽管药物处方相似，但与接受个体化治疗的对照组受试者相比，接受团体治疗的患者A1C、总胆固醇、LDL胆固醇、甘油三酯、收缩压和舒张压、BMI和血清肌酐较低，HDL胆固醇较高（P < 0.001）。健康行为、生活质量和糖尿病知识在团体护理组患者中均优于对照组（均P < 0.001）。集体护理的良好临床、认知和心理结果可以在不同的临床环境中重现。
A trial was performed to establish whether our group care model for lifestyle intervention in type 2 diabetes can be exported to other clinics. This study was a 4-year, two-armed, multicenter controlled trial in 13 hospital-based diabetes clinics in Italy (current controlled trials no. ISRCTN19509463). A total of 815 non–insulin-treated patients aged <80 years with ≥1 year known diabetes duration were randomized to either group or individual care. After 4 years, patients in group care had lower A1C, total cholesterol, LDL cholesterol, triglycerides, systolic and diastolic blood pressure, BMI, and serum creatinine and higher HDL cholesterol (P < 0.001, for all) than control subjects receiving individual care, despite similar pharmacological prescriptions. Health behaviors, quality of life, and knowledge of diabetes had become better in group care patients than in control subjects (P < 0.001, for all). The favorable clinical, cognitive, and psychological outcomes of group care can be reproduced in different clinical settings.
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影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
影响因子：
158.5
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影响因子：
158.5
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影响因子：
16.2
作者：
Trento, M;Passera, P;Porta, M
通讯作者：
Porta, M
影响因子：
16.2
作者：
Trento, M;Passera, P;Porta, M
通讯作者：
Porta, M