Genetics of coxsackievirus B cardiovirulence and inflammatory heart muscle disease.
Genetics of coxsackievirus B cardiovirulence and inflammatory heart muscle disease.
复制标题
柯萨奇 B 型病毒心脏毒力和炎症性心肌病的遗传学。
DOI：
10.1016/0966-842x(96)10026-3
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发表时间：
1996
影响因子：
15.9
通讯作者：
Ramsingh,AI
中科院分区：
文献类型：
--
作者：
Tracy,S;Chapman,NM;Romero,J;Ramsingh,AI
T he SIY coxsackieviruses B (CVBl-6) are iypical human enter0: iruses (Picornaviridae). The yrnomes of CVBt and cTVB3-5 have been completely sed) uenced and, in most c-s, doned as infectious c JNP.-op: es of the genome. The CVB genome is a single molecule of singlestranded, positive-sense. RNA. about 7400 nucleotide:. in length (Fig. 1). The genome codes for four capsid proteins, found in 60 copies each in the virion. as well as the nonstructural proteins necessary fur viral replication. The CVB3 capsid structure’clearly demonstrates its close relationship to other enteroviruses. The diseases associated with coxsackievirus infection are discussed in Box I. co-83
