Informatics in radiology: Electronic cleansing for noncathartic CT colonography: a structure-analysis scheme.
Informatics in radiology: Electronic cleansing for noncathartic CT colonography: a structure-analysis scheme.
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放射学信息学：非导泻 CT 结肠成像的电子清洁：结构分析方案。
DOI：
10.1148/rg.303095154
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Harris,GordonJ
中科院分区：
文献类型：
--
作者：
Cai,Wenli;Yoshida,Hiroyuki;Zalis,MichaelE;Näppi,JanneJohannes;Harris,GordonJ
在不使用泻剂的情况下对粪便进行标记后进行的CT结肠造影术或非泻剂CT结肠造影术(也称为无泻剂CT结肠造影术)被认为是一种很有前途的下一代技术，可以减少或消除与泻剂肠道准备相关的不适，而泻剂肠道准备是进行结肠癌筛查的主要障碍。电子清洗是一种新兴的从CT结肠成像图像中去除标记粪便物质的技术。三种主要的电子清洗伪影-软组织退化、伪软组织结构和不完全清洗-严重损害了电子清洗的非泻剂CT结肠成像图像的质量，并限制了这种模式的诊断用途。开发了一种结构分析电子清洗方案，该方案利用局部形态信息来识别浸没的结肠软组织结构，同时去除标记材料。结合其他尖端图像处理技术，包括局部粗糙度分析、马赛克分解和水平集分割，结构分析清理有助于消除上述伪影，为结肠癌检测提供诊断质量的清理CT结肠癌图像。非泻剂CT结肠造影术结合结构分析净化的应用有望推动CT结肠造影术成为一种患者友好的结直肠癌筛查方法。
Computed tomographic (CT) colonography performed after tagging of fecal matter but without a cathartic agent, or noncathartic CT colonography (also known as laxative-free CT colonography), is regarded as a promising next-generation technique for reducing or eliminating the discomfort associated with cathartic bowel preparation, which is the major barrier to undergoing colon cancer screening. Electronic cleansing is an emerging technique for the removal of tagged fecal materials from CT colonographic images. Three major electronic cleansing artifacts—soft-tissue degradation, pseudo-soft-tissue structures, and incomplete cleansing—severely impair the quality of electronically cleansed noncathartic CT colonographic images and limit the diagnostic utility of this modality. A structure-analysis electronic cleansing scheme was developed that makes use of local morphologic information to identify submerged colonic soft-tissue structures while removing the tagged material. Combined with other cutting-edge image processing techniques, including local roughness analysis, mosaic decomposition, and level set segmentation, structure-analysis cleansing helps eliminate the aforementioned artifacts, providing diagnostic-quality cleansed CT colonographic images for the detection of colon cancer. Noncathartic CT colonography with the application of structure-analysis cleansing is expected to help promote CT colonography as a patient-friendly method of colorectal cancer screening.