MOTOR-ACTIVITY RECORDED IN THE UNPREPARED COLON OF HEALTHY HUMANS

MOTOR-ACTIVITY RECORDED IN THE UNPREPARED COLON OF HEALTHY HUMANS
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DOI:
10.1136/gut.37.5.649
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发表时间:
1995-11-01
期刊:
GUT
影响因子:
24.5
通讯作者:
RAMBAUD, JC
RAMBAUD, JC
中科院分区:
医学1区
文献类型:
--
作者:
LEMANN, M;FLOURIE, B;RAMBAUD, JC

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建立了一种测定人未准备结肠运动的测压方法,并将8名健康受试者的结果与用含有聚乙二醇4000的非吸收溶液(聚乙二醇4000)洗肠后的结果进行了比较。一个长4.5米,12个管腔的管子组件通过鼻子进入并通过胃肠道。每隔一个月进行两次测压记录,一次不做任何准备,另一次在用聚乙二醇清洗肠道后进行。在清洁的结肠中进行的记录之间没有明显的质量差异。未准备的结肠接近清洁的结肠中测量的那些运动指数。然而,高波幅传播收缩的次数(平均(扫描电子显微镜))在清洁的结肠中较高(8.6(2.8)比5.4(1.8)/受试者/9h;p
A manometric method was developed to study the motor activity in the unprepared human colon, and the results in eight healthy subjects were compared with those obtained in the same subjects after bowel cleansing with a non-absorbable solution containing polyethylene glycol 4000 (PEG). A tube assembly (4.5 m long, 12 lumen) was introduced through the nose and passed through the gastrointestinal tract. Two manometric recordings were performed one month apart, one without any preparation and the other after bowel cleansing with PEG. There was no obvious qualitative difference between the recordings performed in the cleansed colon. unprepared colon were close to those motility indices measured in the cleansed colon. The number of high amplitude propagated contractions (mean (SEM)) was, however, higher in the cleansed colon (8.6 (2.8) v 5.4 (1.8)/subject/9 h in the unprepared colon; p