THE OXFORD GRID
THE OXFORD GRID
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DOI：
10.1111/j.1469-1809.1991.tb00394.x
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发表时间：
1991-01-01
影响因子：
1.9
通讯作者：
EDWARDS, JH
中科院分区：
文献类型：
--
作者：
EDWARDS, JH
“牛津网格”是一个术语，用于表示显示来自两个物种的同源基因座的方法。 它也可以被用作与共同祖先有关的历史推断的基础。 这些用途进行了讨论，特别提到人和鼠标。 据推测，只有30个相互易位是足够的，以解释目前的网格定义的差异和端着丝粒核型，通过它的小鼠不同于人类和许多密切相关的啮齿动物，包括大鼠，必须主要通过形成和抑制着丝粒，而不是通过臂间倒位进化。 老鼠和人类是所有哺乳动物中分布最广的，它们的成功似乎与杂食性有关，其行为改变允许广泛的栖息地。
The 'Oxford Grid' is a term used to denote a method of displaying homologous loci from two species. It may also be used as a basis for historical inferences relating to co-ancestry. These uses are discussed with special reference to man and mouse. It is inferred that as few as 30 reciprocal translocations are sufficient to explain the differences defined by the present grid and that the telocentric karyotype, through which the mouse differs from both man and many closely related rodents, including the rat, must have evolved mainly through the formation and suppression of centromeres rather than through pericentric inversions. Mouse and man share the widest distribution of any mammal and their success appears to be related to being omnivorous with behavioural modifications allowing a wide range of habitat.