HYPERTHYROIDISM AS A CLINICAL MANIFESTATION OF A EMBRYONAL CARCINOMA OF THE TESTIS
HYPERTHYROIDISM AS A CLINICAL MANIFESTATION OF A EMBRYONAL CARCINOMA OF THE TESTIS
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DOI：
10.2143/acb.67.3.2062658
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发表时间：
2012-05-01
影响因子：
1.6
通讯作者：
Zuluaga-Gomez, A.
中科院分区：
文献类型：
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作者：
Arrabal-Polo, M. A.;Jimenez-Pacheco, A.;Zuluaga-Gomez, A.
本病例报告描述了一个甲状腺功能亢进症作为胚胎癌的表现，并说明了导致它的原因。该病例描述了一个33岁的男性患者谁主诉胸痛，心悸，轻度呼吸困难，体重减轻。血液分析显示高水平的人绒毛膜促性腺激素（833818 mIU/ml）、T3（16.90 pg/ml）和T4（7.77 ng/dl），以及TSH下降（0.01 μ U/ml）。体格检查和影像学检查证实左侧睾丸肿瘤伴大量肺、肝和腹膜后转移。采用卡比马唑和心得安治疗甲状腺功能亢进症，并进行紧急睾丸切除术;组织学诊断证实为胚胎癌（类器官型），但患者在突发呼吸困难、呼吸急促和快速性心律失常后24小时意外死亡。甲状腺功能亢进症是一种罕见的表现，睾丸肿瘤，应铭记在心，关于病人的生殖学和HCG水平。
This case report describes a case of hyperthyroidism as manifestation of an embryonal carcinoma, and illustrates the causes that led to it. The case describes a 33-year-old male patient who complained of chest pain, palpitations, mild dyspnoea, and weight loss. Blood analysis reveals high levels of human chorionic gonadotropin (833818 mlU/ml), T3 (16.90 pg/ml), and T4 (7.77 ng/dl), as well as a fall of TSH (0.01 ulU/ml). Physical examination and imaging procedures confirm the occurrence of a left testicular tumour associated with numerous lung, hepatic and retroperitoneal metastases. Treatment with carbimazol and propanolol is established to manage hyperthyroidism, and an urgent orchiectomy is performed; the histologic diagnosis confirms an embryonal carcinoma (organoid type), but the patient died unexpectedly 24 hours later after having suffered sudden dyspnoea, tachypnoea, and tachyarrhythmia. Hyperthyroidism is a rare manifestation of a testicular tumour that should be borne in mind with regard to the patient's symptomatology and HCG levels.