Semen quality of Indian welders occupationally exposed to nickel and chromium
Semen quality of Indian welders occupationally exposed to nickel and chromium
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DOI：
10.1016/s0890-6238(03)00040-6
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发表时间：
2003-07-01
影响因子：
3.3
通讯作者：
Grover, P
中科院分区：
文献类型：
--
作者：
Dandevi, K;Rozati, R;Grover, P
对来自南印度一家焊接厂的57名工人和57名对照者的精液质量进行了监测。采用ICP-MS法测定血镍、铬浓度。精液样本的分析是按照世界卫生组织的标准进行的。28名暴露工人的血液中镍和铬含量分别为123.3 +/- 35.2和131.0 +/- 52.6马克/升，显著高于对照组的16.7 +/- 5.8和17.4 +/- 8.9马克/升（n = 27）。暴露工人精子浓度为14.5±2400万/ml，对照组为62.8±4370万/ml。与对照组相比，暴露工人的快速线性精子活力下降。暴露工人尾部缺陷百分率与血镍浓度呈显著正相关。工人精子浓度与血铬含量呈负相关。暴露工人的精液中发现了更多的异常特征。精液异常与接触含镍和铬的焊接烟雾的年数有关。(C) 2003爱思唯尔科学有限公司版权所有。
The semen quality of 57 workers from a welding plant in South India and 57 controls was monitored. Blood nickel and chromium concentrations were determined by ICP-MS. Analysis of semen samples was performed in accordance with World Health Organization criteria. The blood level of nickel and chromium for the 28 exposed workers was 123.3 +/- 35.2 and 131.0 +/- 52.6 mug/l, resepctively, which was significantly higher than the 16.7 +/- 5.8 and 17.4 +/- 8.9 mug/l for the control group (n = 27). Sperm concentrations of exposed workers were 14.5 +/- 24.0 millions/ml and those of the control group were 62.8 +/- 43.7 millions/ml. Rapid linear sperm motility was decreased in exposed workers compared to controls. There was a significant positive correlation between the percentage of tail defects and blood nickel concentration in exposed workers. The sperm concentration showed a negative correlation with blood chromium content in workers. More abnormal characteristics were found in the semen of exposed workers. Semen abnormalities correlated with the number of years of exposure to welding fumes containing nickel and chromium. (C) 2003 Elsevier Science Inc. All rights reserved.