Pulmonary and coronary arterial abnormalities in patients with IgG4-related disease.
Pulmonary and coronary arterial abnormalities in patients with IgG4-related disease.
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DOI：
10.1016/j.radcr.2022.09.070
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发表时间：
2022-12
影响因子：
--
通讯作者：
Little BP
中科院分区：
文献类型：
--
作者：
Cochran RL;Brideau HR;Wu MY;Stone JH;Wallace ZS;Little BP
IgG 4相关疾病（IgG 4-RD）是一种免疫介导的多器官纤维炎性疾病，具有多种临床表现。IgG 4-RD心血管受累被认为是罕见的，在一小部分病例中报告了肺动脉受累。已知的肺动脉表现包括肺动脉炎、肺动脉狭窄和中央肺动脉瘤。在此我们报告2例不同的肺段和亚段肺动脉多灶性扩张的患者，其严重程度不同。2例患者均存在冠状动脉异常。
IgG4-related disease (IgG4-RD) is an immune-mediated multiorgan fibroinflammatory disorder with variable clinical presentations. IgG4-RD cardiovascular involvement is considered rare, with pulmonary arterial involvement reported in a small subset of cases. Known pulmonary artery manifestations include pulmonary arteritis, pulmonary artery stenoses and central pulmonary artery aneurysms. Here we report 2 different patients with multifocal dilatation of the segmental and subsegmental pulmonary arteries with differing degrees of severity. Both patients also had coronary arterial abnormalities.