Cardiorespiratory events in preterm infants: etiology and monitoring technologies
Cardiorespiratory events in preterm infants: etiology and monitoring technologies
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DOI：
10.1038/jp.2015.164
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发表时间：
2016-03-01
影响因子：
2.9
通讯作者：
MacFarlane, P.
中科院分区：
文献类型：
--
作者：
Di Fiore, J. M.;Poets, C. F.;MacFarlane, P.
据估计，每年有1500万婴儿早产（妊娠期< 37周），184个国家的早产率从5%到18%不等。虽然早产率高的原因很多，但一旦出生，婴儿护理的主要挑战包括呼吸和氧合的稳定。这一脆弱婴儿群体的临床护理继续得到改善，但仍有一些主要领域有待解决，包括确定最佳呼吸支持方式和氧饱和度目标，以及减少相关的短期和长期发病率。由于间歇性低氧血症是不成熟的呼吸控制和由此产生的呼吸暂停叠加在不成熟的肺上的结果，因此临床护理的改善必须包括对早产肺发育和早产特有的病理生理学的全面了解。在两部分综述的第1部分中，我们总结了早期肺发育和心肺监测的诊断方法。
Every year, an estimated 15 million infants are born prematurely (< 37 weeks gestation) with premature birth rates ranging from 5 to 18% across 184 countries. Although there are a multitude of reasons for this high rate of preterm birth, once birth occurs, a major challenge of infant care includes the stabilization of respiration and oxygenation. Clinical care of this vulnerable infant population continues to improve, yet there are major areas that have yet to be resolved including the identification of optimal respiratory support modalities and oxygen saturation targets, and reduction of associated short- and long-term morbidities. As intermittent hypoxemia is a consequence of immature respiratory control and resultant apnea superimposed upon an immature lung, improvements in clinical care must include a thorough knowledge of premature lung development and pathophysiology that is unique to premature birth. In Part 1 of a two-part review, we summarize early lung development and diagnostic methods for cardiorespiratory monitoring.