Long term effects on the olfactory system of exposure to hydrogen sulphide

Long term effects on the olfactory system of exposure to hydrogen sulphide
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DOI:
10.1136/oem.56.4.284
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发表时间:
1999-04-01
影响因子:
4.9
通讯作者:
Zavala, G
Zavala, G
中科院分区:
医学2区
文献类型:
--
作者:
Hirsch, AR;Zavala, G

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研究慢性影响硫化氢(H2S)对颅神经I(nervi olfactorii),只有最低限度的描述。方法chemosensitives(嗅觉和味觉)进行了评价,在8名男子抱怨持续功能障碍2-3年后开始职业暴露于H2S。各种双边(两个鼻孔)和单方面(一次一个鼻孔)气味阈值测试与标准的气味剂,以及芝加哥气味测试,一个三气味检测和识别测试和宾夕法尼亚大学的气味识别测试,一系列的40刮和嗅气味识别testsadminister.Results-Six的8例患者表现出不同程度的赤字。两个人在客观测试中得分正常,但认为他们仍然有问题。H2S显然可以导致持续的,有时未被认可的嗅觉deficiency. Conclusion,进一步探讨这些问题的程度,工人暴露于H2S是必要的。
Objective-To study chronic effects of hydrogen sulphide (H2S) on cranial nerve I (nervi olfactorii), which have been only minimally described.Methods-Chemosensations (smell and taste) were evaluated in eight men who complained of continuing dysfunction 2-3 years after the start of occupational exposure to H2S. Various bilateral (both nostrils) and unilateral (one nostril at a time) odour threshold tests with standard odorants as well as the Chicago smell test, a three odour detection and identification test and the University of Pennsylvania smell identification test, a series of 40 scratch and sniff odour identification tests were administered.Results-Six of the eight patients showed deficits of various degrees. Two had normal scores on objective tests, but thought that they continued to have problems. H2S apparently can cause continuing, sometimes unrecognised olfactory deficits.Conclusion-Further exploration into the extent of such problems among workers exposed to H2S is warranted.