Allele frequencies of six miniSTR loci (D20S480, D6S2439, D6S1056, D9S1118, D4S2639 and D17S1290), “Midi-6”, in a Basque Country autochthonous population
Allele frequencies of six miniSTR loci (D20S480, D6S2439, D6S1056, D9S1118, D4S2639 and D17S1290), “Midi-6”, in a Basque Country autochthonous population
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DOI：
10.1016/j.forsciint.2006.08.021
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发表时间：
2007-10
影响因子：
2.2
通讯作者：
Ó. García;I. Yurrebaso;J. Pérez;Raúl Peñas;I. Urieta;I. Uriarte;Pablo Martín;C. Albarrán;A. Alonso;F. J. Inda;Toshimichi Yamamoto
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文献类型：
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作者：
Ó. García;I. Yurrebaso;J. Pérez;Raúl Peñas;I. Urieta;I. Uriarte;Pablo Martín;C. Albarrán;A. Alonso;F. J. Inda;Toshimichi Yamamoto
采用Midi-6六重扩增分型系统，对205名无血缘关系的巴斯克人进行了6个miniSTR常染色体基因座（D20 S480、D 6S 2439、D 6S 1056、D9 S1118、D4 S2639和D17 S1290）的基因频率和法医学参数的检测。没有发现与Hardy-Weinberg预期的显著偏差。由于PCR产物小（< 200 bp），使用这些miniSTR可以增加降解样品可以分型的概率。此外，这些系统可用于需要更多标记物以增加排除能力的常规亲子鉴定分析或复杂亲子鉴定案例（例如涉及密切相关的个体）。© 2006 Elsevier爱尔兰有限公司保留所有权利。
Allele frequencies and forensic parameters for six miniSTR autosomal loci (D20S480, D6S2439, D6S1056, D9S1118, D4S2639 and D17S1290) were obtained from a sample of 205 unrelated Basque autochthous individuals using the recently designed hexaplex amplification and typing system,‘‘Midi-6’’. No significant deviations from Hardy–Weinberg expectations were found. Due to the small PCR products (< 200 bp), the use of these miniSTRs can increase the probability that a degraded sample can be typed. Additionally, these systems can be used in routine paternity analyses where more markers are needed to increase the power of exclusion or in complex paternity cases (eg involving closely related individuals).© 2006 Elsevier Ireland Ltd. All rights reserved.