The split personality of CENP-A nucleosomes.
The split personality of CENP-A nucleosomes.
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DOI:
10.1016/j.cell.2012.07.003
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发表时间:
2012-07-20
期刊:
影响因子:
64.5
通讯作者:
Straight AF
中科院分区:
文献类型:
--
作者:
Westhorpe FG;Straight AF
The composition and structure of centromeric nucleosomes, which contain the histone H3 variant CENP-A, is intensely debated. Two independent studies in this issue, in yeast and human cells, now suggest that CENP-A nucleosomes adopt different structures depending on the stage of the cell cycle.
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