Medical illness burden, trait neuroticism, and depression in older primary care patients.
Medical illness burden, trait neuroticism, and depression in older primary care patients.
复制标题
老年初级保健患者的医疗疾病负担、特质神经质和抑郁症。
DOI：
10.1176/ajp.155.7.969
复制
发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Caine,ED
中科院分区：
文献类型：
--
作者：
Lyness,JM;Duberstein,PR;King,DA;Cox,C;Caine,ED
目的检验医学疾病负担与抑郁独立相关的假设，以及这种关联受神经质调节的假设。方法采用多元回归技术确定从初级保健机构招募的196名60岁及以上受试者的医疗负担和神经质与抑郁症的独立关联。结果医疗负担和神经质与重度抑郁、抑郁症状和精神功能障碍独立相关。结论这些发现支持了医学障碍可能直接导致抑郁症的模型。同时，神经质在晚年抑郁中的作用值得进一步研究。（美国精神病学杂志1998；155:969-971）
OBJECTIVEThe authors tested the hypotheses that medical illness burden is independently associated with depression and that this association is moderated by neuroticism.METHODMultiple regression techniques were used to determine the independent associations of medical burden and neuroticism with depression in a group of 196 subjects, 60 years of age and older, recruited from primary care settings.RESULTSMedical burden and neuroticism were independently associated with major depression, depressive symptoms, and psychiatric dysfunction.CONCLUSIONSThese findings support models in which medical disorders may contribute directly to depression. At the same time, the role of neuroticism in later-life depression warrants further study.(Am J Psychiatry 1998; 155:969–971)