MORPHOLOGY OF PRESUMPTIVE SLOWLY ADAPTING RECEPTORS IN DOG TRACHEA
MORPHOLOGY OF PRESUMPTIVE SLOWLY ADAPTING RECEPTORS IN DOG TRACHEA
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DOI：
10.1002/ar.1092100111
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发表时间：
1984-01-01
影响因子：
--
通讯作者：
KRAUHS, JM
中科院分区：
文献类型：
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作者：
KRAUHS, JM
本文描述了狗气管肌内传入有髓纤维及其终末的三维分支和超微结构。传入末梢被认为是气管的缓慢适应拉伸感受器的末梢。它们具有机械感受器的典型结构特征;在髓鞘丧失的远端，它们的形状变得更加不规则，并且细胞质充满线粒体、糖原和嗜锇体。在某些地方，细胞膜直接附着在基膜上，没有雪旺细胞的介入。一束无髓纤维伴随着每根有髓纤维，并在有髓纤维的末端（管腔）之外继续一段不确定的距离。无髓鞘纤维含有许多圆形、透明的囊泡和少数致密核心囊泡，并且在某些地方也直接附着在基底层上。3-3受体的三维重建显示3个完全不同的分支模式，但都包括明显的环或多或少扭曲的终端区域的一部分（一些神经元显然有一个以上的终端区域）。没有发现明显的结构基础激活受体的横向，而不是纵向拉伸。
The 3-dimensional branching pattern and ultrastructure of afferent myelinated fibers and their terminals located in the trachealis muscle of the dog are described. The afferent endings are believed to be those of the slowly adapting stretch receptors of the trachea. They have structural features typical of mechanoreceptors; distal to the loss of myelin, their shape becomes more irregular and the cytoplasm is filled with mitochondria, glycogen, and osmiophilic bodies. In some places the cell membrane is attached directly to basal lamina without interposition of a Schwann cell. A bundle of unmyelinated fibers accompanies each myelinated fiber and continues for an undetermined distance beyond (luminal to) terminations of the myelinated fiber. The unmyelinated fibers contain many round, clear vesicles and a few dense-cored vesicles and are also attached directly to basal lamina in places. 3-Dimensional reconstruction of 3 receptors revealed 3 quite different branching patterns, but all included apparent rings as part of more or less contorted terminal regions (some neurons apparently having more than one terminal region). No obvious structural basis for the activation of receptors by transverse but not longitudinal stretch was found.