The Economic Burden of Prescription Opioid Overdose, Abuse, and Dependence in the United States, 2013.
The Economic Burden of Prescription Opioid Overdose, Abuse, and Dependence in the United States, 2013.
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DOI：
10.1097/mlr.0000000000000625
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发表时间：
2016-10
期刊：
影响因子：
3
通讯作者：
Xu L
中科院分区：
文献类型：
--
作者：
Florence CS;Zhou C;Luo F;Xu L
重要的是要了解处方阿片类药物过量、滥用和依赖所造成的经济负担的严重程度和分布，以便为临床实践、研究和其他决策者提供信息。选择解决这一流行病方法的决策者需要成本信息来评估其选择的成本效益。从社会角度估计处方阿片类药物过量、滥用和依赖的经济负担 致命的处方阿片类药物过量的发生率来自国家生命统计系统，滥用和依赖的流行率来自国家药物使用和健康调查。致命数据针对的是美国人口，非致命数据是 12 岁及以上美国非收容人口中具有全国代表性的样本。成本数据来自各种来源，包括来自 Truven Health MarketScan® 研究数据库的医疗保健索赔数据，以及来自 WISQARS™（基于网络的伤害统计查询和报告系统）成本模块的致命病例成本。刑事司法费用来自司法部公布的司法支出和就业摘录。对生产力损失的估计是基于之前发表的一项研究。 2013 日历年 致命过量、滥用和处方阿片类药物依赖的货币化负担。总经济负担估计为 785 亿美元。其中三分之一以上（归因于医疗保健和药物滥用治疗费用增加（289 亿美元）。大约四分之一的费用由公共部门承担医疗保健、药物滥用治疗和刑事司法费用。这些估计可以帮助决策者了解与处方阿片类药物使用相关的不良健康后果的严重程度，例如过量、滥用和依赖。
It is important to understand the magnitude and distribution of the economic burden of prescription opioid overdose, abuse and dependence to inform clinical practice, research and other decision makers. Decision makers choosing approaches to address this epidemic need cost information to evaluate the cost effectiveness of their choices. To estimate the economic burden of prescription opioid overdose, abuse, and dependence from a societal perspective Incidence of fatal prescription opioid overdose from the National Vital Statistics System, prevalence of abuse and dependence from the National Survey of Drug Use and Health. Fatal data are for the U.S population, nonfatal data are is a nationally representative sample of the U.S. civilian noninstitutionalized population ages 12 and older. Cost data are from various sources including health care claims data from the Truven Health MarketScan® Research Databases, and cost of fatal cases from the WISQARS™ (Web-based Injury Statistics Query and Reporting System) cost module. Criminal justice costs were derived from the Justice Expenditure and Employment Extracts published by the Department of Justice. Estimates of lost productivity were based on a previously published study. Calendar year 2013 Monetized burden of fatal overdose and abuse and dependence of prescription opioids. The total economic burden is estimated to be $78.5 billion. Over one third of this amount (is due to increased health care and substance abuse treatment costs ($28.9 billion). Approximately one quarter of the cost is borne by the public sector in health care, substance abuse treatment, and criminal justice costs. These estimates can assist decision makers in understanding the magnitude of adverse health outcomes associated with prescription opioid use such as overdose, abuse, and dependence.