Severity of the aggression/anxiety-depression/attention child behavior checklist profile discriminates between different levels of deficits in emotional regulation in youth with attention-deficit hyperactivity disorder.
Severity of the aggression/anxiety-depression/attention child behavior checklist profile discriminates between different levels of deficits in emotional regulation in youth with attention-deficit hyperactivity disorder.
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DOI：
10.1097/dbp.0b013e3182475267
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发表时间：
2012-04
期刊：
影响因子：
--
通讯作者：
Wozniak J
中科院分区：
文献类型：
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作者：
Biederman J;Petty CR;Day H;Goldin RL;Spencer T;Faraone SV;Surman CB;Wozniak J
我们研究了由焦虑/抑郁、攻击和注意力（A-A-A）量表组成的儿童行为检查表（CBCL）的独特特征的严重程度评分（1 SD与2SD）是否有助于区分ADHD儿童的缺陷水平。受试者为197名ADHD儿童和224名非ADHD儿童。我们将情绪自我调节缺陷（DESR）定义为CBCL（CBCL-DESR）的A-A-A量表上的总截止分数>180但<210（1 SD），将严重失调定义为相同量表上的总截止分数≥210（CBCL-严重失调）。所有受试者进行了评估，结构化的诊断访谈和一系列的功能措施。36%的ADHD儿童具有阳性CBCL-DESR特征，对照组为2%（p<0.001），19%的儿童具有阳性CBCL-严重失调特征，对照组为0%（p<0.001）。CBCL-重度调节障碍特征阳性的受试者与CBCL-DESR特征阳性的受试者的选择性差异在于，基线和随访评估时的单相和双相情感障碍、对立违抗性和行为障碍、精神病住院率较高，兄弟姐妹中CBCL-重度调节障碍的发生率较高。相反，与其他ADHD儿童相比，CBCL-DESR与更高的共病破坏性行为，焦虑症和人际功能受损相关。A-A-A CBCL特征的严重程度评分有助于区分ADHD儿童的两组情绪调节问题。
We examined whether severity scores (1SD vs. 2SDs) of a unique profile of the Child Behavior Checklist (CBCL) consisting of the Anxiety/Depression, Aggression, and Attention (A-A-A) scales would help differentiate levels of deficits in children with ADHD. Subjects were 197 children with and 224 without ADHD. We defined deficient emotional selfregulation (DESR) as an aggregate cut-off score of >180 but <210 (1SD) on the A-A-A scales of the CBCL (CBCL-DESR) and Severe Dysregulation as an aggregate cut-off score of ≥210 on the same scales (CBCL-Severe Dysregulation). All subjects were assessed with structured diagnostic interviews and a range of functional measures. 36% of children with ADHD had a positive CBCL-DESR profile vs. 2% of controls (p<0.001) and 19% had a positive CBCL-Severe Dysregulation profile vs. 0% of controls (p<0.001). The subjects positive for the CBCL-Severe Dysregulation profile differed selectively from those with the CBCL-DESR profile in having higher rates of unipolar and bipolar mood disorders, oppositional defiant and conduct disorders, psychiatric hospitalization at both baseline and follow up assessments, and a higher rate of the CBCL-Severe Dysregulation in siblings. In contrast, the CBCL-DESR was associated with higher rates of comorbid disruptive behavior, anxiety disorders, and impaired interpersonal functioning compared to other ADHD children. Severity scores of the A-A-A CBCL profiles can help distinguish two groups of emotional regulation problems in children with ADHD.