Activation of a floral homeotic gene in Arabidopsis
Activation of a floral homeotic gene in Arabidopsis
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DOI：
10.1126/science.285.5427.585
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发表时间：
1999-07-23
期刊：
影响因子：
56.9
通讯作者：
Weigel, D
中科院分区：
文献类型：
--
作者：
Busch, MA;Bomblies, K;Weigel, D
拟南芥花同源异型基因的模式化表达依赖于分生组织身份基因如LEAFY的早期作用，LEAFY编码一种转录因子，决定分生组织是否产生花而不是叶和芽。LEAFY蛋白在整个花中表达，参与同源异型基因的激活，这些基因在花的特定区域表达。同源异型基因AGAMOUS中的LEAFY响应增强子的分析表明，LEAFY与该增强子的直接相互作用是其在植物中的活性所必需的。因此，LEAFY是花同源异型基因的直接上游调节因子。
The patterned expression of floral homeotic genes in Arabidopsis depends on the earlier action of meristem-identity genes such as LEAFY, which encodes a transcription factor that determines whether a meristem will generate flowers instead of Leaves and shoots. The LEAFY protein, which is expressed throughout the flower, participates in the activation of homeotic genes, which are expressed in specific regions of the flower. Analysis of a LEAFY-responsive enhancer in the homeotic gene AGAMOUS indicates that direct interaction of LEAFY with this enhancer is required for its activity in plants. Thus, LEAFY is a direct upstream regulator of floral homeotic genes.