Metastasis to the nasal cavity from primary rectal adenocarcinoma
Metastasis to the nasal cavity from primary rectal adenocarcinoma
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原发性直肠腺癌鼻腔转移
DOI：
10.1007/s12094-009-0325-y
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发表时间：
2009
影响因子：
3.4
通讯作者：
S. Capurro
中科院分区：
文献类型：
--
作者：
C. Conill;M. Vargas;I. Valduvieco;P. Fernández;A. Cardesa;S. Capurro
我们描述一个罕见的情况下转移到鼻窦。该病变的免疫组化（细胞角蛋白20阳性，细胞角蛋白7阴性，p53过表达）和原位杂交（两个病变均未显示p53缺失）与早期直肠腺癌转移一致。膀胱型肿瘤的正确分型需要结合形态学、免疫组化，有时还需要分子分析。
We describe a rare case of metastasis to the paranasal sinuses. The lesion had an immunohistochemical (positivity for cytokeratin 20, negativity for cytokeratin 7, overexpression of p53) andin situhybridisation profile (neither lesions showed deletion for p53) consistent with metastasis from the earlier rectal adenocarcinoma. The correct typification of intestinal-type neoplasms requires a combination of morphological, immunohistochemical and, sometimes, molecular analysis.