PUBERTAL-RELATED CHANGES INFLUENCE THE DEVELOPMENT OF ENVIRONMENT-RELATED SOCIAL-INTERACTION IN THE MALE-RAT
PUBERTAL-RELATED CHANGES INFLUENCE THE DEVELOPMENT OF ENVIRONMENT-RELATED SOCIAL-INTERACTION IN THE MALE-RAT
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DOI：
10.1002/dev.420220608
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发表时间：
1989-09-01
影响因子：
2.2
通讯作者：
KELLOGG, CK
中科院分区：
文献类型：
--
作者：
PRIMUS, RJ;KELLOGG, CK
研究了青春期年龄对熟悉与陌生环境对雄性大鼠社会互动(SI)差异效应的影响。成年大鼠在不熟悉的环境中引起的SI降低被认为是一种焦虑相关反应。于28日龄、35日龄和60日龄分别检测正常雄性大鼠和去势19日龄雄性大鼠的SI。结果显示，在正常大鼠中，在陌生环境中的SI在35天和60天时明显降低，而在28天时则不明显。35d时环境诱导反应的行为成分与60d时不同。青春期前的去势在35天和60天阻止了在陌生环境中SI的下降。这项研究表明，随着青春期的开始，对焦虑性条件的特定行为反应会出现。此外，这种与环境相关的行为反应的发展受到性腺分泌的影响(S)，这表明性腺功能对这种反应的出现是重要的。
The influence of pubertal age on the differential effect of a familiar versus an unfamiliar environment on social interaction (SI) in pairs of male rats was evaluated. The decrease in SI induced by the unfamiliar environment in adult rats is considered an anxiety-related response. Intact male rats and male rats castrated at 19 days were tested for SI at 28, 35, and 60 days of age. The results revealed that in the intact rats, decreased SI in an unfamilar environment was evident at 35 and 60 days but not at 28 days. The behavioral composition of the environment-induced response at 35 days was different from that measured at 60 days. Prepubertal castration prevented the decrease in SI in the unfamiliar environment at both 35 and 60 days. This study demonstrated the emergence with the onset of puberty of a specific behavioral response to an anxiogenic condition. Furthermore, the development of this environment-related behavioral response was influenced by gonadal secretion(s), suggesting the importance of gonadal function to the emergence of this response.