Co-distribution and co-infection of chikungunya and dengue viruses
Co-distribution and co-infection of chikungunya and dengue viruses
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DOI：
10.1186/s12879-016-1417-2
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发表时间：
2016-03-03
影响因子：
3.7
通讯作者：
Yakob, Laith
中科院分区：
文献类型：
--
作者：
Furuya-Kanamori, Luis;Liang, Shaohong;Yakob, Laith
背景：基孔肯雅热和登革热感染在时空上是相关的。目前审查的目的是确定的地理限制基孔肯雅，登革热和主要的蚊子载体的两种病毒，并合成目前流行病学的理解，他们的codistribution.Methods：三个生物医学数据库（PubMed，Scopus和Web的科学）进行了搜索，从成立到2015年5月的研究报告，同时检测基孔肯雅和登革热病毒在同一个病人。此外，从世界卫生组织、疾病预防控制中心和健康地图警报中提取数据，以创建登革热和基孔肯雅病的最新全球分布图。结果：在安哥拉、加蓬、印度、马达加斯加、马来西亚、缅甸、尼日利亚、圣马丁、新加坡、斯里兰卡、坦桑尼亚、泰国和也门发现了基孔肯雅病-登革热合并感染的证据;这些构成只有13的98个国家/地区，其中基孔肯雅和登革热流行/地方性transmissions.Conclusions：了解基孔肯雅登革热合并感染的真实程度是阻碍了目前的诊断主要是基于他们相似的症状。随着美洲正在爆发的基孔肯雅热的到来，公众和公共卫生从业人员对基孔肯雅热的认识提高，预计将提高诊断的准确性。根据新编制的病原体和病媒地理分布清单生成的地图显示了基孔肯雅热和登革热目前的地理界限，以及今后可能受到这两种病毒侵袭的国家/领土。这些描述了共同流行的地区，其中以实验室为基础的诊断疑似病例是更高的优先事项。
Background: Chikungunya and dengue infections are spatio-temporally related. The current review aims to determine the geographic limits of chikungunya, dengue and the principal mosquito vectors for both viruses and to synthesise current epidemiological understanding of their co-distribution.Methods: Three biomedical databases (PubMed, Scopus and Web of Science) were searched from their inception until May 2015 for studies that reported concurrent detection of chikungunya and dengue viruses in the same patient. Additionally, data from WHO, CDC and Healthmap alerts were extracted to create up-to-date global distribution maps for both dengue and chikungunya.Results: Evidence for chikungunya-dengue co-infection has been found in Angola, Gabon, India, Madagascar, Malaysia, Myanmar, Nigeria, Saint Martin, Singapore, Sri Lanka, Tanzania, Thailand and Yemen; these constitute only 13 out of the 98 countries/territories where both chikungunya and dengue epidemic/endemic transmission have been reported.Conclusions: Understanding the true extent of chikungunya-dengue co-infection is hampered by current diagnosis largely based on their similar symptoms. Heightened awareness of chikungunya among the public and public health practitioners in the advent of the ongoing outbreak in the Americas can be expected to improve diagnostic rigour. Maps generated from the newly compiled lists of the geographic distribution of both pathogens and vectors represent the current geographical limits of chikungunya and dengue, as well as the countries/territories at risk of future incursion by both viruses. These describe regions of co-endemicity in which lab-based diagnosis of suspected cases is of higher priority.