A secondary motor area contributing to interlimb coordination during visually guided locomotion in the cat
A secondary motor area contributing to interlimb coordination during visually guided locomotion in the cat
复制标题
猫在视觉引导运动过程中有助于肢体间协调的辅助运动区
DOI：
10.1093/cercor/bhac068
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Drew Trevor
中科院分区：
文献类型：
--
作者：
Nakajima Toshi;Fortier-Lebel Nicolas;Drew Trevor
我们研究了猫交叉沟尾侧皮层4δc区在视觉引导运动控制中的作用。为了做到这一点，我们记录了猫在跑步机上行走并越过障碍物时4δc中114个神经元的活动。共84/114（74%）的细胞是任务相关的，68/84（81%）的这些细胞表现出显着的调制时，对侧肢体的放电频率是第一步的障碍。后者的细胞包括相当大的比例（27/68 - 40%），放电之间的通过对侧前肢和对侧后肢的障碍，这表明该地区的interlimb协调的贡献。我们进一步比较了4δc区的放电与同一细胞结构区（4δr）吻侧区的细胞活动模式，这被认为是一个单独的功能区。尽管在2个分区的活动模式有一些差异，我们认为，在每个活动是兼容的interlimb协调的贡献，他们应该被视为一个单一的功能区，有助于前肢前肢和前肢后肢协调。
We investigated the contribution of cytoarchitectonic cortical area 4δc, in the caudal bank of the cruciate sulcus of the cat, to the control of visually guided locomotion. To do so, we recorded the activity of 114 neurons in 4δc while cats walked on a treadmill and stepped over an obstacle that advanced toward them. A total of 84/114 (74%) cells were task-related and 68/84 (81%) of these cells showed significant modulation of their discharge frequency when the contralateral limbs were the first to step over the obstacle. These latter cells included a substantial proportion (27/68 40%) that discharged between the passage of the contralateral forelimb and the contralateral hindlimb over the obstacle, suggesting a contribution of this area to interlimb coordination. We further compared the discharge in area 4δc with the activity patterns of cells in the rostral division of the same cytoarchitectonic area (4δr), which has been suggested to be a separate functional region. Despite some differences in the patterns of activity in the 2 subdivisions, we suggest that activity in each is compatible with a contribution to interlimb coordination and that they should be considered as a single functional area that contributes to both forelimb–forelimb and forelimb–hindlimb coordination.