Situational Temptation for HIV Medication Adherence in High-Risk Youth
Situational Temptation for HIV Medication Adherence in High-Risk Youth
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DOI：
10.1089/apc.2010.0172
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发表时间：
2011-01-01
影响因子：
4.9
通讯作者：
Huszti, Heather
中科院分区：
文献类型：
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作者：
MacDonell, Karen E.;Naar-King, Sylvie;Huszti, Heather
本研究通过评估参与者在各种情况下对错过药物的诱惑的看法，探讨了情境诱惑（自我效能的一个组成部分）在青少年和年轻人（16-24岁）艾滋病毒药物依从性中的作用。例如，在一个实施例中，当药物引起身体副作用时，当害怕透露艾滋病毒状况时）。青少年（n = 186; 83%的非洲裔美国人）参加了一项多地点临床试验，研究动机干预的有效性。数据收集使用计算机辅助个人访谈。年轻人认为，最有诱惑力的原因或情况可能导致他们错过他们的艾滋病毒药物是症状（如果药物导致你有其他身体症状）和生病（如果药物使你感到恶心或呕吐或如果它尝起来很糟糕），但这些与不遵守没有显着相关性。这表明年轻人对诱惑的期望和与不遵守相关的实际诱惑情况之间存在脱节。与不依从性相关的情境诱惑包括缺乏社会支持，需要暂停服药，以及不需要服药。改善依从性的干预措施应考虑对艾滋病毒药物的看法，特别是服用药物的好处和对身体症状的预期。干预者和临床医生应该考虑可能诱使青少年错过药物剂量的情况，并帮助青少年了解这些诱惑。新兴的方法，如生态瞬时评估（e。例如，在一个实施例中，每日日记、手机短信），可能有助于深入了解感染艾滋病毒的青年的日常经历。
This study explored the role of situational temptation, a component of self-efficacy, in adolescent and young adult (ages 16-24) HIV medication adherence by assessing participants' perceptions of their temptation to miss medications in various situations (e. g., when medication causes physical side effects, when there is fear of disclosure of HIV status). Youth (n = 186; 83% African American) were participants in a multisite clinical trial examining the efficacy of a motivational intervention. Data were collected using computer-assisted personal interviewing. Youth believed the most tempting reasons or situations that might lead them to miss their HIV medications to be symptoms (if the medicine caused you to have other physical symptoms) and sick (if the medicine made you sick to your stomach or made you throw up or if it tasted bad), but these were not significantly associated with nonadherence. This suggests disconnection between youths' expectations of temptation and actual tempting situations associated with nonadherence. Situational temptations associated with nonadherence included lack of social support, needing a break from medications, and not seeing a need for medications. Interventions to improve adherence should consider perceptions of HIV medications, particularly the benefits of taking medications and expectations of physical symptoms. Interventionists and clinicians should consider situations that may tempt youth to miss doses of medication and help youth gain insight into these temptations. Emerging methods, such as Ecological Momentary Assessment (e. g., daily diaries, cell phone text messaging), may be useful in gaining insight into the day-to-day experience of youth living with HIV.