CLINICAL CORRELATION OF HORMONE RECEPTOR STATUS IN EPITHELIAL OVARIAN-CANCER
CLINICAL CORRELATION OF HORMONE RECEPTOR STATUS IN EPITHELIAL OVARIAN-CANCER
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DOI：
10.1016/0090-8258(89)90107-8
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发表时间：
1989-07-01
影响因子：
4.7
通讯作者：
BENRUBI, GI
中科院分区：
文献类型：
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作者：
MASOOD, S;HEITMANN, J;BENRUBI, GI
采用葡聚糖包被活性炭法测定了37例卵巢上皮癌患者治疗前细胞浆雌激素受体（ER）和孕激素受体（PR）水平。68%的肿瘤为ER阳性，49%为PR阳性，41%为两种受体阳性，27%为两种受体阴性。上皮性卵巢癌的受体状态与年龄、产次、种族、吸烟、手术分期、组织学类型、组织学分级、无进展间期或患者生存率相关时，无临床意义。
Cytoplasmic estrogen receptor (ER) and progesterone receptor (PR) levels were measured in ovarian epithelial carcinomas from 37 patients using a dextran-coated charcoal assay prior to any treatment. Sixty-eight percent of the tumors were ER positive, forty-nine percent were PR positive, forty-one percent were positive for both receptors, and twenty-seven percent were negative for both receptors. Receptors status in epithelial ovarian carcinomas was found to have no clinical significance when correlated with age, parity, race, cigarette smoking, surgical stage, histologic type, histologic grade, progression-free interval, or patient survival.