Cardiovascular and respiratory dynamics during normal and pathological sleep
Cardiovascular and respiratory dynamics during normal and pathological sleep
复制标题
DOI：
10.1063/1.2711282
复制
发表时间：
2007-03-01
期刊：
影响因子：
2.9
通讯作者：
Fietze, Ingo
中科院分区：
文献类型：
--
作者：
Penzel, Thomas;Wessel, Niels;Fietze, Ingo
睡眠是一个积极和有规律的过程，对身体和精神状况具有恢复功能。根据脑电波的记录和特征模式和波形的分析，可以区分清醒和五个睡眠阶段。睡眠和睡眠阶段调节自主神经系统功能，如体温、呼吸、血压和心率。这些功能包括通常与激活相关的交感神经张力和通常与抑制相关的副交感神经（或迷走神经）张力。统计物理学的方法用于分析心率和呼吸，以检测睡眠期间自主神经系统的变化。介绍了去趋势波动分析和同步分析及其在健康受试者和睡眠障碍患者睡眠中心率和呼吸的应用。所观察到的变化可用于区分健康受试者的睡眠阶段，以及基于心率和呼吸记录而不直接记录脑电波来区分正常睡眠和干扰睡眠。特别令人感兴趣的是睡眠紊乱的心血管后果，因为它们是心血管疾病的危险因素，如动脉高血压、心脏缺血、心源性猝死和中风。新的衍生变量可以帮助找到这些健康风险的指标。(c)2007年，美国物理学会。
Sleep is an active and regulated process with restorative functions for physical and mental conditions. Based on recordings of brain waves and the analysis of characteristic patterns and waveforms it is possible to distinguish wakefulness and five sleep stages. Sleep and the sleep stages modulate autonomous nervous system functions such as body temperature, respiration, blood pressure, and heart rate. These functions consist of a sympathetic tone usually related to activation and to parasympathetic (or vagal) tone usually related to inhibition. Methods of statistical physics are used to analyze heart rate and respiration to detect changes of the autonomous nervous system during sleep. Detrended fluctuation analysis and synchronization analysis and their applications to heart rate and respiration during sleep in healthy subjects and patients with sleep disorders are presented. The observed changes can be used to distinguish sleep stages in healthy subjects as well as to differentiate normal and disturbed sleep on the basis of heart rate and respiration recordings without direct recording of brain waves. Of special interest are the cardiovascular consequences of disturbed sleep because they present a risk factor for cardiovascular disorders such as arterial hypertension, cardiac ischemia, sudden cardiac death, and stroke. New derived variables can help to find indicators for these health risks. (c) 2007 American Institute of Physics.