Task-induced activation and hemispheric dominance in cerebral circulation during gum chewing
Task-induced activation and hemispheric dominance in cerebral circulation during gum chewing
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DOI：
10.1007/s00415-007-0570-3
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发表时间：
2007-10-01
影响因子：
6
通讯作者：
Hamasaki, Toshimitsu
中科院分区：
文献类型：
--
作者：
Ono, Takahiro;Hasegawa, Yoko;Hamasaki, Toshimitsu
在老年人中，咀嚼功能的维持可能对大脑功能的维持有有益的影响。然而，关于咀嚼过程中脑循环的研究很少。这项研究的目的是验证嚼口香糖时大脑循环的可能增加和大脑半球优势的存在。12名健康的、年轻的、牙列正常的右利手受试者被纳入研究对象。在握手运动和咀嚼口香糖的过程中，测量了双侧大脑中动脉血流速度(MCAV)、心率和动脉二氧化碳水平。咀嚼口香糖时，记录双侧咬肌肌电。运动时MCAV和心率较安静时显著增加。咀嚼口香糖时，工作侧和非工作侧MCAV的增加速度没有差异，但握手练习时，非工作侧的MCAV增加的速度明显大于工作侧。这些结果表明，在咀嚼口香糖的过程中，双侧脑循环增加，而不像握手练习中那样表现出对侧优势。
In elderly persons, it is thought that maintenance of masticatory function may have a beneficial effect on maintenance of cerebral function. However, few studies on cerebral circulation during mastication exist. This study aimed to verify a possible increase in cerebral circulation and the presence of cerebral hemispheric dominance during gum chewing. Twelve healthy, young right-handed subjects with normal dentition were enrolled. Bilateral middle cerebral arterial blood flow velocities (MCAV), heart rate, and arterial carbon dioxide levels were measured during a handgrip exercise and gum chewing. During gum chewing, electromyography of the bilateral masseter muscle was recorded.MCAV and heart rate significantly increased during exercise compared to values at rest.During gum chewing, there were no differences in the rate of increase in MCAV between the working and non-working sides, but during the handgrip exercise, the rate of increase in MCAV was significantly greater for the non-working side than for the working side.During gum chewing,muscle activity on the working side was significantly greater than that on the non-working side. These results suggest that during gum chewing, cerebral circulation increases bilaterally and does not show contralateral dominance, as it does during the handgrip exercise.