Cortisol as a marker for improvement in mindfulness-based stress reduction.
Cortisol as a marker for improvement in mindfulness-based stress reduction.
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DOI：
10.1016/j.ctcp.2009.06.004
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发表时间：
2010-02-01
影响因子：
3
通讯作者：
Pruessner, Jens
中科院分区：
文献类型：
--
作者：
Matousek, Rose H;Dobkin, Patricia L;Pruessner, Jens
虽然很多人都在研究正念减压计划对患者科普各种慢性疾病的能力的有益影响，但大多数研究都依赖于自我报告的改善措施。鉴于这些措施可能无法准确反映生理状况，因此需要一个客观的指标来评估压力管理计划的有益影响。皮质醇是人体组织中主要的压力激素，因此是研究基于正念的减压计划效果的一个有希望的候选措施。结合其他生物措施，使用皮质醇水平作为压力的生理标志物可能有助于验证归因于该计划的自我报告的益处。在目前的手稿中，我们回顾了关于皮质醇作为正念练习改善的生理标志物的作用的现有文献，并对未来的研究设计提出了建议。
While much attention has been devoted to examining the beneficial effects of Mindfulness-Based Stress Reduction programs on patients' ability to cope with various chronic medical conditions, most studies have relied on self-report measures of improvement. Given that these measures may not accurately reflect physiological conditions, there is a need for an objective marker of improvement in research evaluating the beneficial effects of stress management programs. Cortisol is the major stress hormone in the human organism and as such is a promising candidate measure in the study of the effects of Mindfulness-Based Stress Reduction programs. In conjunction with other biological measures, the use of cortisol levels as a physiological marker of stress may be useful to validate self-reported benefits attributed to this program. In the current manuscript, we review the available literature on the role of cortisol as a physiological marker for improvement with regards to mindfulness practice, and make recommendations for future study designs.