Uptake and elimination of polychlorinated arokatic ethers by fish: chloroanisoles
Uptake and elimination of polychlorinated arokatic ethers by fish: chloroanisoles
复制标题
鱼类对多氯芳香醚的吸收和消除：氯苯甲醚
DOI：
10.1016/0045-6535(87)90031-2
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发表时间：
1987
期刊：
影响因子：
8.8
通讯作者：
P. I. Voors
中科院分区：
文献类型：
--
作者：
A. Opperhuizen;P. I. Voors
鱼类对10种氯苯甲醚的吸收速率常数与其他疏水性化学品的吸收速率常数相当。由于发现所有同系物都能快速消除，因此产生的生物浓缩系数低于根据其疏水性预测的值。消除主要是由于在醚键的代谢和速率常数是独立的疏水性。醚键的存在对氯代芳烃的正辛醇/水分配系数影响不大。
Uptake rate constants of 10 chloroanisoles by fish are comparable to those of other hydrophobic chemicals. Since fast elimination is found for all congeners the resulting bioconcentration factors are lower than those predicted from their hydrophobicities. Elimination is mainly due to metabolism at the ether bond and the rate constants are independent of hydrophobicity. The presence of the ether bonds does not influence the octan-1-ol/water partition coefficient of the chlorinated aromatic hydrocarbons significantly.