Analysis of Endoscopic Injectability and Post-Ejection Dripping of Yield Stress Fluids: Laponite, Carbopol and Xanthan Gum
Analysis of Endoscopic Injectability and Post-Ejection Dripping of Yield Stress Fluids: Laponite, Carbopol and Xanthan Gum
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DOI：
10.1252/jcej.21we018
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发表时间：
2021-09-01
影响因子：
0.8
通讯作者：
Ito, Taichi
中科院分区：
文献类型：
--
作者：
Madhavikutty, Athira S.;Ohta, Seiichi;Ito, Taichi
屈服应力流体，其显示可逆的凝胶-溶胶转变和通过剪切降低粘度，预期用于内窥镜应用。然而，尚未从化学工程的角度对这些流体进行定量分析，包括内窥镜导管输送期间的压降和输送后的滴落。在这项研究中，我们制作了一个设备设置，包括内窥镜导管和模型胃肠（GI）管，不同浓度的三个模型屈服应力流体，具体来说，锂皂石（Laponite），卡波姆（CP），和黄原胶（XG），应用和比较。我们阐明了通过导管的压降和GI导管模型上的滴落之间的权衡。在可操作性方面，XG优于CP和XG。重力对滴注的影响，这是受病人的位置，进行了讨论。最后，定量研究了三种材料的粘度、屈服应力和重构时间等流变性能与可操作性的关系。
Yield stress fluids, which show reversible gel-sol transition and a decrease in viscosity via shear, are expected for endoscopic applications. However, quantitative analyses of such fluids, including pressure drop during endoscopic catheter delivery and post-delivery dripping, have not yet been conducted from a chemical engineering perspective. In this study, we fabricated an equipment setup comprising an endoscopic catheter and a model gastrointestinal (GI) duct to which different concentrations of three model yield stress fluids, specifically, laponite (LAP), Carbopol (CP), and xanthan gum (XG), were applied and compared. We clarified the tradeoff between the pressure drop through the catheter and dripping on the GI duct model. In terms of operability, LAP performed better than CP and XG. The effect of gravity on dripping, which is greatly affected by the position of a patient, was discussed. Finally, the relationship between the operability and rheological properties such as viscosity, yield stress, and restructuring time of the three materials were quantitatively studied.