Observation of suspected choroidal and ciliary body melanomas for evidence of growth prior to enucleation.
Observation of suspected choroidal and ciliary body melanomas for evidence of growth prior to enucleation.
复制标题
观察疑似脉络膜和睫状体黑色素瘤在摘除前的生长证据。
DOI：
10.1016/s0161-6420(80)35200-7
复制
发表时间：
1980
期刊：
影响因子：
13.7
通讯作者：
J. Donald M. Gass
中科院分区：
文献类型：
--
作者：
J. Donald M. Gass
116名疑似脉络膜睫状体恶性黑色素瘤的患者在摘除眼球前观察了肿瘤生长的证据。所有患者在发现肿瘤后至少随访五年。69名患者肿瘤未能生长，没有发现转移性黑色素瘤的证据。肿瘤生长47例，摘除35例。5例(4例摘除)死于转移性黑色素瘤。其他原发恶性肿瘤(9例)和其他原因(11例)造成的死亡人数超过了黑色素瘤。预测中小疑似黑色素瘤生长的临床准确率约为75%。5名患者死于转移性黑色素瘤。这项研究没有证据表明，在摘除眼球前观察小肿瘤以寻找生长的证据会导致死亡率增加。
One hundred and sixteen patients with suspected malignant melanoma of the choroid and ciliary body were observed for evidence of tumor growth prior to enucleation. All patients were followed for a minimum of five years after tumor detection. The tumor failed to grow in 69 patients, and none developed evidence of metastatic melanoma. The tumor grew in 47 patients, and 35 patients had enucleation. Five patients (4 having enucleation) died of metastatic melanoma. Deaths caused by other primary malignancies (9 patients) and other causes (11 patients) outnumbered those caused by melanomas. The clinical accuracy of predicting growth of small and medium suspected melanomas was approximately 75%. Five patients died because of metastatic melanoma. This study demonstrated no evidence of increased mortality caused by observation of small tumors for evidence of growth prior to enucleation.