Pediatric mechanical circulatory support: future directions.

Pediatric mechanical circulatory support: future directions.
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儿科机械循环支持:未来方向。

DOI:
10.1097/pcc.0b013e318292e562
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发表时间:
2013
期刊:
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
影响因子:
--
通讯作者:
MacLaren,Graeme
MacLaren,Graeme
中科院分区:
--
文献类型:
--
作者:
Dalton,HeidiJ;Dodge-Khatami,Ali;MacLaren,Graeme

文献摘要

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体外支持领域正在迅速发展。新技术、改进的各种患者体验以及先前被排除在体外生命支持之外的群体的成功结果正在增加该技术在患者支持中的使用。尽管初步的结果报告令人鼓舞,但它们通常取自单中心报告或大型数据库,没有具体细节来回答许多相关问题或不反映新技术影响的时代。研究人员之间的合作、严格的科学数据收集和分析以及接受体外生命支持的患者的仔细的短期和长期结果对于避免不当使用这种高资源、高成本的技术并确定新设备和技术的有效性至关重要。出血和血栓形成仍然是毁灭性的并发症,减少并发症和改善抗凝治疗方案或消除抗凝治疗的需要的努力将对该领域产生重大益处。
The field of extracorporeal support is moving forward rapidly. New technology, improved experience with a variety of patients, and successful outcomes in groups previously excluded from extracorporeal life support are increasing the use of this technique in patient support. Although initial reports of outcome are encouraging, they are often taken from single-center reports or large databases without specific detail to answer many of the relevant questions or for eras that do not reflect the effects of new technology. Collaboration between investigators, rigorous scientific data collection and analysis, and careful short-and long-term outcomes for patients receiving extracorporeal life support are imperative to avoid improper use of this high-resource, high-cost technology and to establish the efficacy of new devices and techniques. Bleeding and thrombosis remain devastating complications and efforts to reduce complications and improve anticoagulation regimens or eliminate the need for anticoagulation would be of major benefit to the field.