Efficient synthesis of polysubstituted isochromanones via a novel photochemical rearrangement.
Efficient synthesis of polysubstituted isochromanones via a novel photochemical rearrangement.
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DOI：
10.1039/c1cc14269k
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发表时间：
2011-09
影响因子：
4.9
通讯作者：
W. Xia;Yutian Shao;Weijun Gui;C. Yang
中科院分区：
文献类型：
--
作者：
W. Xia;Yutian Shao;Weijun Gui;C. Yang
介绍了一种新的、简便的合成多取代异色罗曼酮的方法。紫外光在苯溶液中照射2-甲酰基苯烯衍生物，其产率可达98%。提出了可能的反应机理，并得到了同位素实验的进一步支持。
A novel and convenient approach to the synthesis of polysubstituted isochromanones is described. Irradiation of 2-formyl phenylalkeno-derivatives with UV light in benzene solution afforded the corresponding products in up to 98% yield. The possible reaction mechanism is proposed and further supported by the isotopic experiments.