A MATRIX ANALYSIS FOR A CONJUGATE VESTIBULO-OCULAR REFLEX
A MATRIX ANALYSIS FOR A CONJUGATE VESTIBULO-OCULAR REFLEX
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DOI：
10.1007/bf00332912
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发表时间：
1988-01-01
影响因子：
1.9
通讯作者：
TWEED, D
中科院分区：
文献类型：
--
作者：
VILIS, T;TWEED, D
采用矩阵分析的方法比较了前庭神经元和眼神经元之间产生共轭前庭眼反射（VOR）的连通性。该技术表明，连接通常是解剖对称的。该技术还用于确定VOR内保持共轭性的适应类型和位点。适应分为1）由视觉反馈的变化引起的适应，这需要VOR或系统特定的变化，以及2）由运河或肌肉的变化产生的适应，这需要缺陷特定的适应。在前一种情况下，适应最好是通过前庭运动神经元投射的附加改变来实现的。在后一种情况下，适当的适应将是一系列倍增的变化，在前庭神经元的水平上应用时，运河故障或在运动神经元的水平上的眼睛的肌肉受损。因此，分析表明VOR内有多个可塑性位点，专门用于适应不同的缺陷。
The technique of matrix analysis is used to compare the connectivity between vestibular neurons and oculomotor neurons of the two eyes that would generate a conjugate vestibulo-ocular reflex (VOR). The technique shows that the connectivity is normally anatomically symmetric. The technique is also used to determine the types and loci of adaptation within the VOR that will maintain conjugacy. Adaptation is divided into 1) that evoked by changes in visual feedback, which requires VOR or system-specific changes and 2) that produced by changes in the canals or muscles, which requires deficit-specific adaptation. In the former case, the adaptation could best be achieved by an additive alteration of the vestibular-motoneuron projections. In the latter case, the appropriate adaptations would be serial multiplicative changes, applied at the level of the vestibular neurons when the canals are at fault or at the level of the motoneurons of the eye whose muscles are impaired. The analysis thus suggests multiple loci of plasticity within the VOR, specialized for adapting to different deficits.