NOMENCLATURE OF LIPOXINS AND RELATED-COMPOUNDS DERIVED FROM ARACHIDONIC-ACID AND EICOSAPENTAENOIC ACID
NOMENCLATURE OF LIPOXINS AND RELATED-COMPOUNDS DERIVED FROM ARACHIDONIC-ACID AND EICOSAPENTAENOIC ACID
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DOI：
10.1016/0090-6980(87)90243-7
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发表时间：
1987-08-01
影响因子：
2.9
通讯作者：
SAMUELSSON, B
中科院分区：
文献类型：
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作者：
SERHAN, CN;WONG, PYK;SAMUELSSON, B
花生四烯酸和二十碳五烯酸的氧化衍生物，其含有共轭四烯结构并且是非环化的C2O羧酸，首先从人和猪白细胞中分离和表征（Serhan，C.N.等人，1984，Biochem.Biophys.Res.Commun.118, 943-949；Wong,P.Y.-K.等人， 1985，生物化学研究。126，765-775。属于这些系列中的每一个的化合物都被引入了俗名“脂氧素”和“脂氧烯”。在此，我们建议将衍生自花生四烯酸的含四烯化合物称为四系列脂氧素(LX)(即脂氧素A4或LXA4和脂氧素B4或LXB4)，而衍生自二十碳五烯酸的化合物称为五系脂氧素(即脂氧素A5或LXA5和脂氧素B5或LXB5)。
Oxygenated derivatives of arachidonic acid and eicosapentaenoic acid which contain conjugated tetraene structure and are non-cyclized C2O carboxylic acids were first isolated and characterized from human and porcine luekocytes (Serhan, C.N. et al, 1984, Biochem. Biophys. Res. Commun. 118, 943-949; Wong, P.Y.-K., et al, 1985, Biochem. Biophys. Res. Commun. 126, 765-775). The trivial names lipoxins and lipoxenes have been introduced for compounds belonging to each of these series. Here, we propose that tetraene-containing compounds derived from arachidonic acid be denoted as lipoxins (LX) of the four series (i.e. lipoxin A4 or LXA4 and lipoxin B4 or LXB4) and those derived from eicosapentaenoic be termed lipoxins of the five series, (i.e. lipoxin A5 or LXA5 and lipoxin B5 or LXB5).