Antibiotic resistance in soil and water environments
Antibiotic resistance in soil and water environments
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DOI：
10.1080/09603120220129292
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发表时间：
2002-06-01
影响因子：
3.2
通讯作者：
Ike, J
中科院分区：
文献类型：
--
作者：
Esiobu, N;Armenta, L;Ike, J
使用改良的琼脂稀释技术筛选了7个地点的耐药性细菌。对高水平抗生素耐药的分离株进行r质粒筛选。对氨苄青霉素、青霉素、四环素、万古霉素和链霉素普遍存在低水平耐药（25 μ g ml（-1）），但对卡那霉素不存在。耐药群体在高抗生素水平下急剧下降，表明内在的非紧急机制是造成低剂量下表现出的多重耐药的原因。奶牛场粪便中的磷含量显著高于对照组（P
Seven locations were screened for antibiotic-resistant bacteria using a modified agar dilution technique. Isolates resistant to high levels of antibiotics were screened for r plasmids. Low-level resistance (25 mug ml(-1)) was widespread for ampicillin, penicillin, tetracycline, vancomycin and streptomycin but not for kanamycin. Resistant populations dropped sharply at high antibiotic levels, suggesting that intrinsic non-emergent mechanisms were responsible for the multiple drug resistance exhibited at low doses. Dairy farm manure contained significantly (P