Background pathology of the common marmoset (Callithrix jacchus) in toxicological studies
Background pathology of the common marmoset (Callithrix jacchus) in toxicological studies
复制标题
DOI：
10.1016/j.etp.2006.02.013
复制
发表时间：
2006-07-01
影响因子：
--
通讯作者：
Habermann, G.
中科院分区：
文献类型：
--
作者：
Kaspareit, J.;Friderichs-Gromoll, S.;Habermann, G.
对200只普通绒猴(Callithrix Jacchus)进行了组织病理学检查，以评估该物种的自发病变谱。常见表现为肾上腺、肝、肾、脾髓外造血，十二指肠囊性布伦纳腺，大肠和胆囊炎，肾脏矿化和色素沉着，肝细胞空泡化，微小肉芽肿和糖原储存，垂体囊肿，甲状腺C细胞增生和淋巴细胞灶，卵巢黄体增生症和各器官炎性细胞灶。(C)2006年爱思唯尔股份有限公司。版权所有。
Two hundred common marmosets (Callithrix jacchus) from control groups (100 males, 100 females) of toxicological studies were examined histopathologically to evaluate the spectrum of spontaneous lesions in this species. Frequent findings were extramedullary hematopoiesis affecting adrenal glands, liver, kidney and spleen, cystic Brunner's glands in the duodenum, acute or subacute inflammation in the large intestine and gall bladder, renal mineralization and pigmentation, hepatic Ito-cell vacuolation, microgranuloma and glycogen storage, pituitary cysts, C-cell hyperplasia and lymphocytic foci of the thyroid gland, luteal hyperplasia of the ovary and inflammatory cell foci in various organs. (c) 2006 Elsevier GmbH. All rights reserved.