Quantifying transmission of Campylobacter jejuni in commercial broiler flocks.
Quantifying transmission of Campylobacter jejuni in commercial broiler flocks.
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DOI：
10.1128/aem.01912-08
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发表时间：
2009-01-01
影响因子：
4.4
通讯作者：
Klinkenberg, D.
中科院分区：
文献类型：
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作者：
Gerwe, T. van;Miflin, J. K.;Klinkenberg, D.
由于来自家禽的肉被弯曲杆菌属定殖。是细菌性胃肠炎的主要原因，应通过预防肉鸡群的定植等措施减少人类接触。为了更深入地了解弯曲杆菌引入肉鸡群的可能来源，必须估计鸡群中第一只鸡被定殖的时间。如果已知鸡群内的传播率，则可以根据鸡群中定居鸟类的流行率随时间的变化来确定这种估计。本研究的目的是确定弯曲杆菌的传播率，使用现场收集的数据为5年的澳大利亚肉鸡群。我们使用了42个空肠弯曲杆菌定殖群的独特采样数据，并估计了传播率，传播率定义为每天一只定殖鸟引起的继发感染数量。估计每只传染病禽每天有2.37 0.295例感染，这意味着在我们的研究群体中，由20，000只肉鸡组成的定居群将在第一只肉鸡定居后4.4至7.2天内使群内患病率增加至95%。使用贝叶斯分析，在研究中的所有鸡群中，鸡群中第一只鸡的定殖时刻估计为21日龄以上。本研究提供了一个重要的定量估计弯曲杆菌在肉鸡群中的传播率，这可能是有益的，在该领域的弯曲杆菌的流行病学研究的未来。©American Society for Microbiology. All rights reserved.
Since meat from poultry colonized with Campylobacter spp. is a major cause of bacterial gastroenteritis, human exposure should be reduced by, among other things, prevention of colonization of broiler flocks. To obtain more insight into possible sources of introduction of Campylobacter into broiler flocks, it is essential to estimate the moment that the first bird in a flock is colonized. If the rate of transmission within a flock were known, such an estimate could be determined from the change in the prevalence of colonized birds in a flock over time. The aim of this study was to determine the rate of transmission of Campylobacter using field data gathered for 5 years for Australian broiler flocks. We used unique sampling data for 42 Campylobacter jejuni-colonized flocks and estimated the transmission rate, which is defined as the number of secondary infections caused by one colonized bird per day. The estimate was 2.37 0.295 infections per infectious bird per day, which implies that in our study population colonized flocks consisting of 20,000 broilers would have an increase in within-flock prevalence to 95% within 4.4 to 7.2 days after colonization of the first broiler. Using Bayesian analysis, the moment of colonization of the first bird in a flock was estimated to be from 21 days of age onward in all flocks in the study. This study provides an important quantitative estimate of the rate of transmission of Campylobacter in broiler flocks, which could be helpful in future studies on the epidemiology of Campylobacter in the field. ©American Society for Microbiology. All rights reserved.