Blood lipid distributions in older persons. Prevalence and correlates of hyperlipidemia.
Blood lipid distributions in older persons. Prevalence and correlates of hyperlipidemia.
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DOI：
10.1016/1047-2797(92)90032-l
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发表时间：
1992-01-01
影响因子：
5.6
通讯作者：
Colsher, P L
中科院分区：
文献类型：
--
作者：
Wallace, R B;Colsher, P L
本文介绍了爱荷华州71至102岁农村老年人群的血液总胆固醇、甘油三酯、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇水平的分布。从横向来看，女性的总胆固醇和低密度脂蛋白水平高于男性，随着年龄的增长，这一水平有所下降。女性的平均高密度脂蛋白水平也高于男性，但在整个年龄范围内保持相对稳定。在长期护理机构居住的参与者中，年龄和性别特定的总胆固醇、低密度脂蛋白和高密度脂蛋白水平较低。高密度脂蛋白而不是总胆固醇水平在吸烟者和患有慢性病、身体依赖和身体功能测试表现较差的人中较低，而在饮酒者中较高。如果符合国家胆固醇教育计划的筛查指南，这些人群中的大多数总胆固醇水平达到或超过5.2 mmol/L(200 mg/dL)，将需要进一步评估可能的高脂血症。
Distributions of blood total cholesterol, triglyceride, low-density-lipoprotein (LDL) cholesterol, and high-density-lipoprotein (HDL) cholesterol levels are presented for a geographically defined cohort of rural elderly Iowans, 71 to 102 years old. Cross-sectionally, women had higher levels of total and LDL cholesterol than men did, levels that declined with increasing age. Mean HDL cholesterol levels were also higher in women than in men, but remained relatively constant across the age range. Age- and sex-specific total, LDL, and HDL cholesterol levels were lower among participants residing in long-term-care facilities. HDL but not total cholesterol levels were lower in cigarette smokers and those with chronic illnesses, physical dependence, and poorer performance on physical function tests, and higher among those consuming alcohol. If subjected to the screening guidelines of the National Cholesterol Education Program, a majority of this population, having total cholesterol levels of 5.2 mmol/L (200 mg/dL) or higher, would require further evaluation for possible hyperlipidemia.