Heart atria granularity effects of changes in water-electrolyte balance.
Heart atria granularity effects of changes in water-electrolyte balance.
复制标题
水电解质平衡变化对心房粒度的影响。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
A. J. Bold
中科院分区：
文献类型：
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作者：
A. J. Bold
摘要使用一种新的形态测量方法对接受已知会改变水电解质平衡的程序的大鼠进行心房粒度测量。研究发现，缺水和缺钠会导致心房颗粒过多，而在饮用水中联合服用去氧皮质酮（2.5 mg/100 g 体重/天）和 2% NaCl 会导致脱颗粒。缺水时心房颗粒度与血细胞比容值之间存在统计学上显着的相关性。血细胞比容较高的动物有更多的颗粒。研究结果指出了在这些情况下心房特异性颗粒与水电解质平衡调节之间的关系。
SummaryAtrial granularity was measured using a new morphometric method in rats subjected to procedures known to alter water-electrolyte balance. It was found that water deprivation and sodium deficiency lead to atrial hypergranulation, whereas, the combined administration of desoxycorticosterone (2.5 mg/100 g body wt/day) and 2% NaCl in the drinking water leads to degranulation. A statistically significant correlation was found between atria granularity and hematocrit values in water deprivation; animals with higher hematocrit had more granules. The findings point to a relationship between atrial-specific granules and the regulation of water-electrolyte balance in these situations.