"The Burden of Pregnancy"; heavier for the heaviest? The changes in Health Related Quality of Life (HRQoL) assessed by the 15D instrument during pregnancy and postpartum in different body mass index groups: a longitudinal survey
"The Burden of Pregnancy"; heavier for the heaviest? The changes in Health Related Quality of Life (HRQoL) assessed by the 15D instrument during pregnancy and postpartum in different body mass index groups: a longitudinal survey
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DOI：
10.1111/aogs.13068
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发表时间：
2017-03-01
影响因子：
4.3
通讯作者：
Roine, Risto P.
中科院分区：
文献类型：
--
作者：
Sahrakorpi, Niina;Koivusalo, Saila B.;Roine, Risto P.
导言。关于健康相关生活质量(HRQOL)及其在正常妊娠过程中的变化的信息很少。我们研究了不同体重指数(BMI)组孕妇在孕期和产后1年期间的HRQOL变化。材料和方法。750名在怀孕14周前接受第一次超声波检查的孕妇被邀请参加一项以社区为基础的纵向调查。参与者根据他们的BMI被分成三组，=30 kg/m(2)。这些女性被要求填写问卷，评估基线时的HRQL(15D)、抑郁症状(爱丁堡抑郁量表，EPDS)、医疗、产科和社会经济状况。分别于孕30周、产后6周、3个月和12个月复查HRQOL和EPDS。结果。在被邀请的750名母亲中，325名(43%)回复了调查问卷和至少一份后续调查问卷。在基线时，平均15D得分随着体重指数的增加而下降，但当调整年龄、教育程度、胎次或EPDS得分时，差异并不具有统计学意义(0.929，0.921和0.916，p=0.16)。在妊娠期间，所有女性的HRQOL都有所下降，但肥胖组的下降幅度(-0.088；95%CI-0.110至-0.065)显著高于其他组[-0.054(95%CI-0.062至-0.045)和-0.051(95%CI-0.068至-0.033)，P=0.019]。在产后3个月内，所有BMI组的平均HRQOL恢复到基线水平，无论分娩方式或与妊娠相关的并发症。结论。对于最重的人来说，怀孕的负担更重。
Introduction. Only little information is available on health-related quality of life (HRQoL) and its changes during the course of a normal pregnancy. We studied changes in HRQoL in a pregnant population during pregnancy and until 1 year postpartum in different body mass index (BMI) groups. Material and methods. Seven hundred and fifty pregnant women attending the first ultrasound examination before gestational week 14 were invited to participate in a longitudinal, communal-based survey. The participants were divided into three groups according to their BMI; = 30 kg/m(2). The women were asked to fill in questionnaires assessing HRQoL (15D), depressive symptoms (Edinburgh Depression Scale, EPDS), medical, obstetric and socioeconomic status at baseline. HRQoL and EPDS were re-assessed at 30 weeks of gestation, and 6 weeks, 3 and 12 months postpartum. Results. Of the invited 750 mothers, 325 (43%) returned the questionnaires and at least one follow-up questionnaire. At baseline, mean 15D scores decreased with increasing BMI but the difference was not statistically significant when adjusted for age, educational attainment, parity or EPDS-scores (0.929, 0.921 and 0.916, p = 0.16). During the course of pregnancy, the HRQoL of all women decreased but this decrease was significantly greater in the obese group (-0.088; 95% CI -0.110 to -0.065) than in the other groups [-0.054 (95% CI -0.062 to -0.045) and -0.051 (95% CI -0.068 to -0.033), p = 0.019]. Within 3 months postpartum the mean HRQoL recovered in all BMI groups to baseline levels, irrespective of the mode of delivery or pregnancy-related complications. Conclusion. The burden of pregnancy is heavier for the heaviest.