Cognitive Behavioral Stress Management for Healthy Women at Risk for Breast Cancer: a Novel Application of a Proven Intervention.
Cognitive Behavioral Stress Management for Healthy Women at Risk for Breast Cancer: a Novel Application of a Proven Intervention.
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DOI：
10.1007/s12160-015-9726-z
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发表时间：
2015-12
期刊：
影响因子：
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通讯作者：
Ceballos RM
中科院分区：
文献类型：
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作者：
McGregor BA;Dolan ED;Murphy KM;Sannes TS;Highland KB;Albano DL;Ward AA;Charbonneau AM;Redman MW;Ceballos RM
有患乳腺癌风险的女性报告心理困扰增加，这与癌症相关的行为和生物学负相关。本研究旨在探讨一个为期10周的认知行为压力管理（CBSM）小组干预对有乳腺癌家族史的妇女的痛苦的影响。参与者被随机分配到CBSM组（N= 82）或等候名单对照组（N=76）。采用层次回归法检验CBSM对抑郁症状和感知压力的基线至干预后影响。CBSM参与者报告治疗后抑郁症状（β= - 0.17, p<0.05）和感知压力（β= - 0.23, p<0.05）显著低于等候名单组参与者。此外，更多的放松练习预示着更低的痛苦。基于群体的CBSM干预是可行的，可以减少有乳腺癌家族史的女性的心理困扰。目前的研究结果为CBSM的未来应用提供了一条令人鼓舞的途径。（Clinicaltrials.gov编号NCT00121160）
Women at risk for breast cancer report elevated psychological distress, which has been adversely associated with cancer-relevant behaviors and biology. The present study sought to examine the effects of a 10-week cognitive behavioral stress management (CBSM) group intervention on distress among women with a family history of breast cancer. Participants were randomly assigned to CBSM (N= 82) or a wait-list comparison group (N=76). Baseline to post-intervention effects of CBSM on depressive symptoms and perceived stress were examined using hierarchical regression. CBSM participants reported significantly lower post-treatment depressive symptoms (β=−0.17, p<0.05) and perceived stress (β= − 0.23, p<0.05) than wait-list comparison participants. Additionally, greater relaxation practice predicted lower distress. Group-based CBSM intervention is feasible and can reduce psychological distress among women with a family history of breast cancer. The present findings represent an encouraging avenue for the future application of CBSM. (Clinicaltrials.gov number NCT00121160)