Neutron generator at Hiroshima University for use in radiobiology study.
Neutron generator at Hiroshima University for use in radiobiology study.
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广岛大学用于放射生物学研究的中子发生器。
DOI：
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发表时间：
1995
影响因子：
2
通讯作者：
E. Iwamoto
中科院分区：
文献类型：
--
作者：
S. Endo;M. Hoshi;H. Tauchi;S. Takeoka;K. Kitagawa;S. Suga;N. Maeda;K. Komatsu;S. Sawada;E. Iwamoto
在广岛大学放射生物学和医学研究所建造了一台用于放射生物学研究的中子发生器。质子能量高达3 MeV的7Li(p,n)7 Be反应产生能量小于1.3 MeV的单能中子。质子被一个申克尔型加速器加速并轰击到7li靶上。设计并将制造一种用于辐照生物材料（如小鼠、培养细胞等）的装置。中子和伽马射线剂量率通过配对（TE-TE和C-CO2）电离室测量。当使用10微米厚的7Li作为靶材时，伽马射线的污染小于6%。在距离靶10 cm处，组织等效材料的最大剂量率为40 cGy/min。用3he气体比例计数器测量了所得中子的能量分布。薄7Li或7LiF靶产生的单能中子在0.1 ~ 1.3 MeV的能量范围内，能量分布较小，约为50 keV（高斯宽度为1 σ）。当入射质子能量为2.3 MeV时，中子的能量扩散约为10%或更少。我们发现HIRRAC产生小的能量扩散中子，并且剂量率足够用于放射生物学研究。
A neutron generator (HIRRAC) for use in radiobiology study has been constructed at the Research Institute for Radiation Biology and Medicine, Hiroshima University (RIRBM). Monoenergetic neutrons of which energy is less than 1.3 MeV are generated by the 7Li(p,n)7 Be reaction at proton energies up to 3 MeV. The protons are accelerated by a Schenkel-type-accelerator and are bombared onto the 7Li-target. An apparatus for the irradiation of biological material such as mice, cultured cells and so on, was designed and will be manufactured. Neutron and gamma-ray dose rates were measured by paired (TE-TE and C-CO2) ionization chambers. Contamination of the gamma ray was less than about 6% when using 10-microns-thick 7Li as a target. Maximum dose rates for the tissue equivalent materials was 40 cGy/min at a distance of 10 cm from the target. Energy distributions of the obtained neutrons have been measured by a 3He-gas proportional counter. The monoenergetic neutrons within an energy region from 0.1 to 1.3 MeV produced by thin 7Li or 7LiF targets had a small energy spread of about 50 keV (1 sigma width of gaussian). The energy spread of neutrons was about 10% or less at an incident proton energy of 2.3 MeV. We found that HIRRAC produces small energy spread neutrons and at sufficient dose rates for use in radiobiology studies.
C3H 10T1/2 小鼠细胞的中子能量依赖性致癌转化。
影响因子：
3.4
作者：
Miller,RC;Geard,CR;Brenner,DJ;Komatsu,K;Marino,SA;Hall,EJ
通讯作者：
Hall,EJ