Effect of food consistency on the degree of mineralization in the rat mandible
Effect of food consistency on the degree of mineralization in the rat mandible
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DOI：
10.1007/s10439-007-9330-x
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发表时间：
2007-09-01
影响因子：
3.8
通讯作者：
van Eijden, Theo M. G. J.
中科院分区：
文献类型：
--
作者：
Tanaka, Eiji;Sano, Ryota;van Eijden, Theo M. G. J.
改用软食，与咀嚼过程中施加到下颌骨的力减少相关，可能会导致下颌骨矿化程度的改变。这种改变可能因地区而异。本研究的目的是通过检查喂食硬质或软质饮食的生长大鼠下颌骨的矿化程度来分析这种变化。本研究使用了 15 只 Wistar 雄性大鼠。断奶后，六只老鼠喂硬食，其余九只老鼠喂软食。 9周后，使用 microCT 系统获得了下颌骨皮质骨和小梁骨的三维重建。测定髁突中的小梁骨以及下颌体前部和后部区域的皮质骨的矿化程度。在两个饮食组中，小梁的矿化程度均显着低于皮质骨（p < 0.01）。在下颌体中，两个饮食组中前部区域的矿化程度显着高于后部区域（p < 0.01）。在这两个区域中，软饮食组的矿化程度显着高于硬饮食组（p < 0.05 或 0.01）。硬饮食组髁突中的骨小梁的矿化程度显着高于软饮食组（p < 0.01）。目前的结果表明适当的咀嚼肌功能对于颅面生长和发育的重要性。
A switch to a soft diet, associated with reduced forces applied to the mandible during mastication, may result in an alteration of the degree of mineralization in the mandible. This alteration may be regionally different. The aim of this study was to analyze this alteration by examination of the degree of mineralization in the mandible of growing rats fed with a hard or soft diet. Fifteen Wistar male rats were used in this investigation. After weaning, six rats were fed with a hard diet and the remaining nine rats with a soft diet. After 9 weeks, three-dimensional reconstructions of the cortical and trabecular bone of their mandibles were obtained using a microCT system. The degree of mineralization was determined for the trabecular bone in the condyle and for the cortical bone in the anterior and posterior areas of the mandibular body. In both diet groups the degree of mineralization was significantly (p < 0.01) lower in the trabecular than in the cortical bone. In the mandibular body, the anterior area showed a significantly (p < 0.01) higher degree of mineralization than the posterior area in both diet groups. In both areas the soft diet group had a significantly (p < 0.05 or 0.01) higher degree of mineralization than the hard diet group. The trabecular bone in the condyle of the hard diet group showed a significantly (p < 0.01) higher degree of mineralization than in the soft diet group. The present results indicate the importance of proper masticatory muscle function for craniofacial growth and development.