Prevalence of Comorbidities in Patients with Chronic Obstructive Pulmonary Disease
Prevalence of Comorbidities in Patients with Chronic Obstructive Pulmonary Disease
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DOI：
10.1159/000281880
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发表时间：
2010-01-01
期刊：
影响因子：
3.7
通讯作者：
Biscione, Gianluca
中科院分区：
文献类型：
--
作者：
Cazzola, Mario;Bettoncelli, Germano;Biscione, Gianluca
背景：慢性阻塞性肺疾病（COPD）与许多合并症相关，但COPD患者并发合并症的比例尚未明确定义。目的：我们旨在通过意大利全科医生学院（SIMG）拥有的健康搜索数据库（HSD）获取的信息来研究COPD与合并症之间的关系，该数据库存储了约1.5%的意大利全科医生服务人口的信息。方法：我们利用HSD获得的信息进行了一项基于人群的回顾性研究。软件系统使用第九版《国际疾病分类》对所有诊断记录进行编码。结果：与非COPD患者相比，COPD患者发生心血管事件的风险增加[缺血性心脏病（一般人群为6.9%，COPD患者为13.6%）、心律失常（一般人群为6.6%，COPD患者为15.9%）、心力衰竭（一般人群为2.0%，COPD患者为7.9%）和其他形式的心脏病（一般人群为10.7%，COPD患者为23.1%）；老年人COPD的影响更高]；非精神病性精神障碍，包括抑郁症（一般人群29.1%，COPD患者41.6%；COPD对< 75岁女性的影响更高）；糖尿病（普通人群10.5%，COPD患者18.7%）；骨质疏松症（普通人群为10.8%，COPD患者为14.8%），COPD对< 75岁女性的影响更高，以及恶性肺肿瘤（普通人群为0.4%，COPD患者为1.9%）。结论：我们的研究结果表明，COPD是这些合并症的危险因素。版权所有：S. Karger AG，巴塞尔
Background: Chronic obstructive pulmonary disease (COPD) is associated with many comorbidities, but the percentage of COPD patients who develop comorbidities has not been clearly defined.Objectives: We aimed to examine the relationship between COPD and comorbidities using information obtained from the Health Search Database (HSD) owned by the Italian College of General Practitioners (SIMG), which stores information on about 1.5% of the total Italian population served by general practitioners.Methods: We conducted a population-based retrospective study using information obtained from the HSD. The software system used codes all the diagnostic records using the 9th Revision of the International Classification of Diseases.Results: Compared to the non-COPD people, COPD patients were at increased risk for cardiovascular events [ischemic heart disease (6.9% in the general population vs. 13.6% in COPD patients), cardiac arrhythmia (6.6% in the general population vs. 15.9% in COPD patients), heart failure (2.0% in the general population vs. 7.9% in COPD patients), and other forms of heart disease (10.7% in the general population vs. 23.1% in COPD patients); with a higher impact of COPD in the elderly]; non-psychotic mental disorders, including depressive disorders (29.1% in the general population vs. 41.6% in COPD patients; with a higher impact of COPD on women aged < 75 years); diabetes mellitus (10.5% in the general population vs. 18.7% in COPD patients); osteoporosis (10.8% in the general population vs. 14.8% in COPD patients), with a higher impact of COPD on women aged < 75 years, and malignant pulmonary neoplasms (0.4% in the general population vs. 1.9% in COPD patients).Conclusions: Our results indicate that COPD is a risk factor for these comorbid conditions. Copyright (C) 2010 S. Karger AG, Basel