Portable sick house syndrome gas monitoring system based on novel colorimetric reagents for the highly selective and sensitive detection of formaldehyde
Portable sick house syndrome gas monitoring system based on novel colorimetric reagents for the highly selective and sensitive detection of formaldehyde
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DOI：
10.1021/es0305050
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发表时间：
2003-12-15
影响因子：
11.4
通讯作者：
Suzuki, K
中科院分区：
文献类型：
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作者：
Suzuki, Y;Nakano, N;Suzuki, K
室内家具和墙壁释放的甲醛（HCHO）会伤害眼睛、鼻子和呼吸器官，并引起过敏，这被称为“生病综合症”。设计合成了具有胺酮结构的新型比色HCHO传感分子KD-XA01和KD-XA02，并利用KD-XA01研制了一种手持式室内HCHO气体监测仪器。这些传感分子在温和的条件下产生由无色到黄色的快速颜色变化，这是由于试剂中的漆胺酮结构与HCHO反应生成一种lutidine衍生物。这种反应不仅发生在溶液中，也发生在固相（纤维素纸表面）。为了利用这一现象，我们开发了一种方便快速的监测系统，用于检测室内HCHO气体，该系统使用高灵敏度和选择性检测片，该检测片由多孔纤维素纸制成，其中含有硅胶作为吸附剂，KD-XA01，在最佳条件下使用磷酸。该仪器检测片剂表面颜色由白色到黄色的变化，并监测片剂表面颜色随LED （475 nm）反射光强度的变化。在一定采样时间和流速下，响应与HCHO浓度成正比；低于世界卫生组织标准值0.05 ppm的HCHO在5分钟内就被检测出来。检出限为0.005 ppm。该监测系统不受羰基化合物（如乙醛和丙酮）、醇类、碳氢化合物和典型气体（如一氧化碳、二氧化碳、二氧化氮等）的干扰，这有助于正确测量HCHO浓度。使用该仪器可以监测新公寓和学校房间的HCHO气体；反应值与标准DNPH法得到的结果吻合良好。这种高灵敏度，选择性和方便的HCHO气体监测仪广泛适用于非该领域专家的用户。
Formaldehyde (HCHO) emitted from the furniture and the walls in the rooms injures the eyes, nose, and respiratory organs and causes allergies, which is called sick house syndrome. We designed and synthesized novel colorimetric HCHO-sensing molecules (KD-XA01 and KD-XA02) which possess an enaminone structure and developed a hand-held instrument to monitor indoor HCHO gas with the use of KD-XA01. These sensing molecules produced speedy color changes from colorless to yellow under mild conditions, which was caused by the fact that the enaminone structure in the reagent reacts with HCHO to give a lutidine derivative. This reaction took place not only in the solution phase but also in the solid phase (surface of the cellulose paper). To take advantage of this phenomena a handy and rapid monitoring system has been developed for detecting indoor HCHO gas using a highly sensitive and selective detection tablet constructed from the porous cellulose paper that contains silica gel as an adsorbent, KD-XA01, and phosphoric acid under optimum conditions. This instrument detected the surface color change of the tablet from white to yellow, which was monitored as a function of the intensity of the reflected light illuminated by an LED (475 nm). The response was proportional to the HCHO concentration at a constant sampling time and flow rate; 0.05 ppm HCHO, which is under the standard value set by the World Health Organization, was able to be detected in 5 min. The detection limit was 0.005 ppm. This monitoring system was not interfered by carbonyl compounds such as acetaldehyde and acetone, alcohols, hydrocarbons, and typical gases such as carbon monoxide, carbon dioxide, nitrogen dioxide, etc., which contributes to the measurement of correct HCHO concentrations. It was possible to monitor the HCHO gas in the room of a new apartment and school using this instrument; the response values were in good agreement with those obtained by the standard DNPH method. This highly sensitive, selective, and handy HCHO gas monitor is widely applicable and convenient for users who are not specialists in this field.